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n-acetylaspartic acid and Autosomal Dominant Cerebellar Ataxia, Type II

n-acetylaspartic acid has been researched along with Autosomal Dominant Cerebellar Ataxia, Type II in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bushara, KO; Deelchand, DK; Eberly, LE; Emir, UE; Gomez, CM; Hutter, D; Joers, JM; Lyu, T; Öz, G1
Arsovic, A; Auburger, G; Bosman, LWJ; Canet-Pons, J; Chae, WH; De Zeeuw, CI; Gispert, S; Halbach, MV; Kaya, ZE; Meierhofer, D; Mittelbronn, M; Pilatus, U; Rollmann, E; Seidel, K; Sen, NE1
Brandt, AU; Doss, S; Endres, M; Oberwahrenbrock, T; Paul, F; Rinnenthal, JL1
Clark, HB; Demirgöz, D; Eberly, LE; Kittelson, E; Orr, HT; Öz, G; Rainwater, O1
Adanyeguh, IM; Brice, A; Deelchand, DK; Durr, A; Eberly, LE; Emir, UE; Henry, PG; Jauffret, C; Mochel, F; Nguyen, TM; Öz, G; Rinaldi, D; Valabregue, R1
Brandt, AU; Doss, S; Endres, M; Klockgether, T; Lux, S; Maul, S; Minnerop, M; Papazoglou, S; Paul, F; Rinnenthal, JL; Schmitz-Hübsch, T; Würfel, J1
Bushara, KO; Clark, HB; Eberly, LE; Gomez, CM; Gross, MD; Hutter, D; Jiang, H; Oz, G; Tkác, I1
Chen, HC; Lirng, JF; Soong, BW; Wang, PS; Wu, HM; Wu, YT1
Belli, G; Cosottini, M; De Grandis, D; Della Nave, R; Filla, A; Foresti, S; Ginestroni, A; Guerrini, L; Lolli, F; Mascalchi, M; Piacentini, S; Plasmati, R; Salvi, F; Siciliano, G; Tessa, C1
Färkkilä, M; Häkkinen, AM; Harno, H; Heikkinen, S; Kallela, M; Kaunisto, MA; Lundbom, N; Wessman, M1
Ishikawa, K; Nakano, I; Nakao, K; Shimazaki, H; Takiyama, Y1
Boesch, SM; Felber, S; Schocke, M; Seppi, K; Wenning, GK; Wolf, C1
Borkert, J; Döhlinger, S; Hauser, TK; Luft, AR; Schulz, JB1
Aichner, FT; Boesch, SM; Bürk, K; Felber, S; Fornai, F; Hollosi, P; Poewe, W; Schocke, M1

Trials

1 trial(s) available for n-acetylaspartic acid and Autosomal Dominant Cerebellar Ataxia, Type II

ArticleYear
Differentiation of SCA2 from MSA-C using proton magnetic resonance spectroscopic imaging.
    Journal of magnetic resonance imaging : JMRI, 2007, Volume: 25, Issue:3

    Topics: Adult; Age of Onset; Aged; Aspartic Acid; Cerebellum; Choline; Creatine; Diagnosis, Differential; Female; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple System Atrophy; Reference Values; Severity of Illness Index; Spinocerebellar Ataxias; Time Factors

2007

Other Studies

13 other study(ies) available for n-acetylaspartic acid and Autosomal Dominant Cerebellar Ataxia, Type II

ArticleYear
Neurochemical abnormalities in premanifest and early spinocerebellar ataxias.
    Annals of neurology, 2018, Volume: 83, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Aspartic Acid; Ataxins; Brain; Brain Diseases, Metabolic; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Disease Progression; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Spinocerebellar Ataxias; Young Adult

2018
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.
    Neurobiology of disease, 2019, Volume: 132

    Topics: Acetyltransferases; Animals; Aspartic Acid; Ataxin-2; Brain; Female; Gene Knock-In Techniques; Male; Mice; Mice, Transgenic; Spinocerebellar Ataxias; Trinucleotide Repeats

2019
Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.
    Cerebellum (London, England), 2014, Volume: 13, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Brain; Cerebral Cortex; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Nerve Fibers, Myelinated; Spinocerebellar Ataxias

2014
Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology.
    Neurobiology of disease, 2015, Volume: 74

    Topics: Animals; Area Under Curve; Aspartic Acid; Ataxin-1; Cerebellum; Doxycycline; Gene Expression; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Mice, Transgenic; Motor Activity; Polymerase Chain Reaction; Recovery of Function; ROC Curve; Rotarod Performance Test; Sensitivity and Specificity; Spinocerebellar Ataxias

2015
In vivo neurometabolic profiling in patients with spinocerebellar ataxia types 1, 2, 3, and 7.
    Movement disorders : official journal of the Movement Disorder Society, 2015, Apr-15, Volume: 30, Issue:5

    Topics: Adult; Aspartic Acid; Ataxins; Cohort Studies; Female; Glutamic Acid; Humans; Machado-Joseph Disease; Magnetic Resonance Spectroscopy; Male; Middle Aged; Principal Component Analysis; Protons; Spinocerebellar Ataxias; Statistics as Topic

2015
Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency.
    Journal of neurology, 2015, Volume: 262, Issue:8

    Topics: Adult; Aged; Aspartic Acid; Cerebellum; Cerebral Cortex; Creatine; Female; Glutamic Acid; Glutathione; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Spinocerebellar Ataxias

2015
Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Jul-15, Volume: 25, Issue:9

    Topics: Analysis of Variance; Aspartic Acid; Brain Chemistry; Case-Control Studies; Female; Functional Laterality; Glial Fibrillary Acidic Protein; Humans; Inositol; Isoprostanes; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Protons; Severity of Illness Index; Spinocerebellar Ataxias; Statistics as Topic

2010
Association between proton magnetic resonance spectroscopy measurements and CAG repeat number in patients with spinocerebellar ataxias 2, 3, or 6.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adult; Age of Onset; Aged; Aspartic Acid; Case-Control Studies; Cerebellum; Creatine; Disease Progression; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Tissue Proteins; Research Design; Retrospective Studies; Severity of Illness Index; Spinocerebellar Ataxias; Taiwan; Trinucleotide Repeats

2012
Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study.
    Brain : a journal of neurology, 2004, Volume: 127, Issue:Pt 8

    Topics: Adult; Aged; Aspartic Acid; Biomarkers; Brain Stem; Cerebellum; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pons; Severity of Illness Index; Spinocerebellar Ataxias

2004
Decreased cerebellar total creatine in episodic ataxia type 2: a 1H MRS study.
    Neurology, 2005, Feb-08, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Calcium Channels; Cerebellum; Child; Choline; Creatine; Dysarthria; Female; Humans; Lactates; Magnetic Resonance Spectroscopy; Male; Nystagmus, Pathologic; RNA Splice Sites; Spinocerebellar Ataxias

2005
[A case of spinocerebellar ataxia type 6 with its initial symptom of episodic ataxia-like phenotype].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:1

    Topics: Adult; Aspartic Acid; Brain Chemistry; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Spinocerebellar Ataxias

2006
Magnetic resonance imaging in spinocerebellar ataxias.
    Cerebellum (London, England), 2008, Volume: 7, Issue:2

    Topics: Aspartic Acid; Ataxin-1; Ataxin-3; Ataxins; Atrophy; Brain; Cerebellum; Humans; Magnetic Resonance Imaging; Nerve Tissue Proteins; Nuclear Proteins; Repressor Proteins; Sensitivity and Specificity; Spinocerebellar Ataxias

2008
Proton magnetic resonance spectroscopic imaging reveals differences in spinocerebellar ataxia types 2 and 6.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 13, Issue:4

    Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mutation; Protons; Spinocerebellar Ataxias; Statistics, Nonparametric

2001