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n-acetyl-4-s-cysteaminylphenol and Melanoma

n-acetyl-4-s-cysteaminylphenol has been researched along with Melanoma in 10 studies

*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferguson, J; Kelland, LR; Pearson, VC; Robins, DJ; Rogers, PM1
Ferguson, J; Kelland, LR; Robins, DJ; Rogers, PM1
Kelland, LR; Lant, N; Nicoll, K; Robertson, J; Robins, DJ; Rogers, PM1
Iwashina, T; Jimbow, K; Wiebe, LI1
Jimbow, K1
Cao, H; Jimbow, K; Kishi, H; Ota, M; Singh, S; Thomas, PD; Yamashita, T1
Gili, A; Jimbow, K; Ota, M; Thomas, PD1
Kelland, LR; Lant, NJ; McKeown, P; Robins, DJ; Rogers, PM1
Bloomer, WD; Prezioso, JA; Wang, N1
Bloomer, WD; Epperly, MW; Prezioso, JA; Wang, N1

Other Studies

10 other study(ies) available for n-acetyl-4-s-cysteaminylphenol and Melanoma

ArticleYear
Synthesis and antimelanoma activity of tertiary amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2003, Volume: 13, Issue:11

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cysteamine; Humans; Melanoma; Phenols; Protein Structure, Tertiary

2003
Synthesis and antimelanoma activity of sterically congested tertiary amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2005, Volume: 15, Issue:2

    Topics: Agaricales; Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteamine; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Melanins; Melanoma; Models, Chemical; Monophenol Monooxygenase; Nitrogen; Oxygen; Phenols; Stereoisomerism; Sulfides; Time Factors; Ultraviolet Rays

2005
Synthesis and antimelanoma activity of reversed amide analogues of N-acetyl-4-S-cysteaminylphenol.
    Oncology research, 2006, Volume: 16, Issue:2

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cysteamine; Humans; Melanoma; Molecular Structure; Phenols; Structure-Activity Relationship

2006
The synthesis of N-acetyl-4-S-cysteaminyl [U-14C]phenol as a basis for the development of an antimelanoma and melanoma-radioimaging agent.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 1994, Volume: 45, Issue:6

    Topics: Acetylation; Antineoplastic Agents; Carbon Radioisotopes; Cysteamine; Isotope Labeling; Melanoma; Models, Chemical; Phenols; Radionuclide Imaging

1994
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1998
Selective incorporation and specific cytocidal effect as the cellular basis for the antimelanoma action of sulphur containing tyrosine analogs.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cystamine; Cysteamine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; HeLa Cells; Humans; Melanoma; Mice; Monophenol Monooxygenase; Phenols

1999
Comparison of in vitro cytotoxicity of N-acetyl and N-propionyl derivatives of phenolic thioether amines in melanoma and neuroblastoma cells and the relationship to tyrosinase and tyrosine hydroxylase enzyme activity.
    Melanoma research, 2000, Volume: 10, Issue:1

    Topics: Amides; Antineoplastic Agents; Cell Division; Cystamine; Cysteamine; Growth Inhibitors; HeLa Cells; Humans; Melanoma; Monophenol Monooxygenase; Neuroblastoma; Phenols; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2000
Synthesis and antimelanoma activity of analogues of N-acetyl-4-S-cysteaminylphenol.
    Anti-cancer drug design, 2000, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Cell Division; Cysteamine; Growth Inhibitors; Humans; Melanoma; Phenols; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Agents; Cell Division; Cell-Free System; Cysteamine; DNA; Humans; Kinetics; Leucovorin; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Tetrazolium Salts; Theophylline; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured

1992
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
    Cancer letters, 1992, Mar-31, Volume: 63, Issue:1

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cysteamine; Drug Synergism; Humans; Melanoma; Methionine Sulfoximine; Monophenol Monooxygenase; Phenols; Theophylline; Time Factors; Tumor Cells, Cultured

1992