Compounds > n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea

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n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and Melanoma

n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea has been researched along with Melanoma in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (50.00)	18.2507
2000's	5 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bacin, F; Cellarier, E; Chollet, P; D'Incan, M; Durando, X; Farges, MC; Madelmont, JC; Mouret-Reynier, MA; Thivat, E; Vasson, MP	1
Debiton, E; Glasser, AL; Madelmont, JC; Marchenay, C; Maurizis, JC; Rolhion, C	1
Chollet, P; Cure, H; D'Incan, M; Durando, X; Madelmont, JC; Mouret-Reynier, MA; Souteyrand, P; Thivat, E	1
Chollet, P; D'Incan, M; Durando, X; Madelmont, JC; Sinsard, A; Thivat, E	1
Barthomeuf, C; Cellarier, E; Chollet, P; D'Incan, M; Demidem, A; Durando, X; Farges, MC; Thivat, E; Vasson, MP	1
Baudry, JP; Cussac, C; Dupuy, JM; Godeneche, D; Madelmont, JC; Maurizis, JC; Mounetou, E; Rapp, M; Sauzieres, J; Veyre, A	1
Adenis, A; Chauvergne, J; Chevallier, B; Chollet, P; Fargeot, P; Fumoleau, P; Kerbrat, P; Lentz, MA; Roche, H; Urosevic, V	1
Cussac-Buchdhal, C; Debiton, E; Dupuy, JM; Madelmont, JC; Maurizis, JC; Mounetou, E; Rapp, M; Veyre, A	1
Buchdahl, C; Debiton, E; Glasser, AL; Laval, F; Madelmont, JC; Mounetou, E; Rolhion, C	1
Chollet, P; Cure, H; D'incan, M; Fargeot, P; Fumoleau, P; Hanauske, A; Lentz, MA; Ouabdesselam, R; Ravaud, A; Roche, H; Souteyrand, P; Viens, P	1

Trials

5 trial(s) available for n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and Melanoma

Article	Year
Phase II trial of the association of a methionine-free diet with cystemustine therapy in melanoma and glioma. Anticancer research, 2009, Volume: 29, Issue:12 Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Choroid Neoplasms; Combined Modality Therapy; Diet; Female; Glioma; Humans; Male; Maximum Tolerated Dose; Melanoma; Methionine; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Nutritional Status; Prognosis; Survival Rate; Treatment Outcome	2009
Second-line chemotherapy of disseminated malignant melanoma with cystemustine at 60 mg/m2: a phase II trial. Anti-cancer drugs, 2005, Volume: 16, Issue:9 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Female; Humans; Male; Melanoma; Middle Aged; Nausea; Neoplasm Metastasis; Neutropenia; Nitrosourea Compounds; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting	2005
Optimal methionine-free diet duration for nitrourea treatment: a Phase I clinical trial. Nutrition and cancer, 2008, Volume: 60, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Female; Glioma; Humans; Male; Melanoma; Methionine; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Nutritional Status; Oligodendroglioma; Patient Compliance; Treatment Outcome	2008
Results of a phase II trial with cystemustine in advanced malignant melanoma. A trial of the EORTC Clinical Screening Group. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Skin Neoplasms	1996
Results of a phase II trial with cystemustine at 90 mg/m(2) as a first- or second-line treatment in advanced malignant melanoma: a trial of the EORTC Clinical Studies Group. Melanoma research, 1999, Volume: 9, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Dacarbazine; Female; Humans; Immunotherapy; Male; Melanoma; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Treatment Outcome	1999

Other Studies

5 other study(ies) available for n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and Melanoma

Article	Year
Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells. Melanoma research, 2002, Volume: 12, Issue:5 Topics: Animals; Apoptosis; Carmustine; Cattle; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylnitrosourea; Guanosine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Time Factors; Tumor Cells, Cultured	2002
Long-term disease-free survival in advanced melanomas treated with nitrosoureas: mechanisms and new perspectives. BMC cancer, 2005, Nov-15, Volume: 5 Topics: Adult; Antineoplastic Agents; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Remission Induction; Skin Neoplasms; Time Factors; Treatment Outcome	2005
Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Animals; Antineoplastic Agents; Drug Resistance; Female; Guanosine; Humans; Melanoma; Methyltransferases; Mice; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured	1994
Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma. British journal of cancer, 1997, Volume: 76, Issue:9 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Guanosine; Humans; Injections, Intravenous; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors; Tumor Cells, Cultured	1997
Melanoma-cell toxicity of cystemustine combined with O6-benzyl-N2-acetylguanosine. Melanoma research, 1998, Volume: 8, Issue:2 Topics: Antineoplastic Agents; Cell Survival; DNA Damage; Drug Synergism; Enzyme Inhibitors; Guanosine; Humans; Melanocytes; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Tumor Cells, Cultured	1998