n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea has been researched along with B16 Melanoma in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demidem, A; Guénin, S; Morvan, D; Stepien, G; Thivat, E | 1 |
| Demidem, A; Madelmont, JC; Morvan, D | 1 |
| Demidem, A; Morvan, D | 1 |
| Demidem, A; Guénin, S; Madelmont, JC; Morvan, D; Poignet, A; Schwartz, L; Steyaert, JM | 1 |
| Croisy, A; Guerquin-Kern, JL; Labarre, P; Madelmont, JC; Maurizis, JC; Mounetou, E; Papon, J; Rapp, M; Wu, TD | 1 |
| Bourges, M; Buchdahl, C; Communal, Y; Madelmont, JC; Papon, J | 1 |
| De Latour, M; Demidem, A; Madelmont, JC; Morvan, D; Papon, J | 2 |
8 other study(ies) available for n'-(2-chloroethyl)-n-(2-(methylsulfonyl)ethyl)-n'-nitrosourea and B16 Melanoma
| Article | Year |
|---|---|
Combined methionine deprivation and chloroethylnitrosourea have time-dependent therapeutic synergy on melanoma tumors that NMR spectroscopy-based metabolomics explains by methionine and phospholipid metabolism reprogramming.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Antineoplastic Agents; Body Weight; Cell Proliferation; Combined Modality Therapy; Confidence Intervals; Growth Inhibitors; Liver; Male; Melanoma, Experimental; Metabolome; Methionine; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Nuclear Magnetic Resonance, Biomolecular; Organ Size; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Random Allocation; Stress, Physiological; Time Factors; Tumor Burden | 2009 |
Response of melanoma tumor phospholipid metabolism to chloroethyle nitrosourea: a high resolution proton NMR spectroscopy study.
Topics: Animals; Antineoplastic Agents; Cell Survival; Ethanolamines; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorylcholine | 2003 |
Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloroethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Drug Resistance, Neoplasm; Inactivation, Metabolic; Magnetic Resonance Spectroscopy; Male; Melanoma, Experimental; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Models, Biological; Neoplasm Transplantation; Nitrosourea Compounds; Proteomics; Treatment Outcome; Tumor Cells, Cultured | 2007 |
PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment.
Topics: Animals; Antineoplastic Agents; DNA Damage; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Okadaic Acid; Pentosephosphates; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase | 2008 |
A new O6-alkylguanine-DNA alkyltransferase inhibitor associated with a nitrosourea (cystemustine) validates a strategy of melanoma-targeted therapy in murine B16 and human-resistant M4Beu melanoma xenograft models.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Melanoma, Experimental; Mice; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Reproducibility of Results; Xenograft Model Antitumor Assays | 2008 |
G2 accumulation and melanin overproduction in malignant melanocytes treated with a new nitrosourea.
Topics: Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Melanins; Melanoma, Experimental; Mice; Microscopy, Electron; Monophenol Monooxygenase; Nitrosourea Compounds; Time Factors; Tumor Cells, Cultured | 1998 |
Cystemustine induces redifferentiation of primary tumors and confers protection against secondary tumor growth in a melanoma murine model.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasms, Second Primary; Nitrosourea Compounds; Nuclear Magnetic Resonance, Biomolecular; Tumor Cells, Cultured | 2001 |
Melanoma tumors acquire a new phospholipid metabolism phenotype under cystemustine as revealed by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy of intact tumor samples.
Topics: Animals; Antineoplastic Agents; Cell Division; Choline; Ethanolamines; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nitrosourea Compounds; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorylcholine; Protons | 2002 |