n-(4-carboxyphenyl)retinamide and Carcinoma--Squamous-Cell

n-(4-carboxyphenyl)retinamide has been researched along with Carcinoma--Squamous-Cell* in 1 studies

Other Studies

1 other study(ies) available for n-(4-carboxyphenyl)retinamide and Carcinoma--Squamous-Cell

ArticleYear
[Effect of RII on the biological properties of human nasopharyngeal carcinoma cell lines].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1995, Volume: 17, Issue:5

    N(4-hydroxycarbophenyl) retinamide (RII) is a new synthetic analog of retinoids with low toxicity. Its effect on the biological properties associated with tumor malignant behavior of human nasopharyngeal carcinoma cell lines (HNCs), including CNE-2Z parent cell lines and their variants L2, H2, L4 was studied. RII (10(-5) mol/L) caused detectable morphologic differentiation of HNCs. It inhibited growth of HNCs in vitro and decreased ability of these cells to penetrate matrigel-coated filters by using a reconstituted basement membrane invasion assay. These results suggested that RII might be a kind of useful anticancer drug.

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Humans; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Tretinoin; Tumor Cells, Cultured

1995