n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide has been researched along with Breast Neoplasms in 3 studies
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide: calmodulin antagonist; structure given in first source
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide : A sulfonamide that is 5-chloronaphthalene-2-sulfonamide in which one of the hydrogens of the nitrogen atom is substituted by a 4-aminobutyl group.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of anticalmodulin agents, namely trifluoperazine (TFP) and two naphthalene sulfonamide derivatives (W-7 and W-13), were tested on the growth of a human breast cancer cell line (MDA-MB-231) using a soft agar clonogenic assay." | 7.66 | Inhibition of human breast cancer colony formation by anticalmodulin agents: trifluoperazine, W-7, and W-13. ( Hickie, RA; Klaassen, DJ; Wei, JW, 1983) |
| "Estrogen receptor (ER)-negative human breast cancer cell lines (MDA-MB-231 and MDA-MB-435) and ER-positive derivatives of the MCF-7 cell line selected for growth in the presence of antiestrogens (LY2 and RR) were used as in vitro models of tamoxifen-resistant human breast cancer in this study." | 5.28 | Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. ( Peterson, VA; Strobl, JS, 1992) |
| "The effects of anticalmodulin agents, namely trifluoperazine (TFP) and two naphthalene sulfonamide derivatives (W-7 and W-13), were tested on the growth of a human breast cancer cell line (MDA-MB-231) using a soft agar clonogenic assay." | 3.66 | Inhibition of human breast cancer colony formation by anticalmodulin agents: trifluoperazine, W-7, and W-13. ( Hickie, RA; Klaassen, DJ; Wei, JW, 1983) |
| "Estrogen receptor (ER)-negative human breast cancer cell lines (MDA-MB-231 and MDA-MB-435) and ER-positive derivatives of the MCF-7 cell line selected for growth in the presence of antiestrogens (LY2 and RR) were used as in vitro models of tamoxifen-resistant human breast cancer in this study." | 1.28 | Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. ( Peterson, VA; Strobl, JS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, JW | 1 |
| Hickie, RA | 1 |
| Klaassen, DJ | 1 |
| Strobl, JS | 2 |
| Peterson, VA | 2 |
| Woodfork, KA | 1 |
3 other studies available for n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide and Breast Neoplasms
| Article | Year |
|---|---|
Inhibition of human breast cancer colony formation by anticalmodulin agents: trifluoperazine, W-7, and W-13.
Topics: Breast Neoplasms; Calmodulin; Cell Division; Cell Line; Female; Humans; Sulfonamides; Trifluoperazin | 1983 |
A survey of human breast cancer sensitivity to growth inhibition by calmodulin antagonists in tissue culture.
Topics: Breast Neoplasms; Calmodulin; Culture Techniques; Drug Resistance; Humans; Imidazoles; Receptors, Es | 1994 |
Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13.
Topics: Breast Neoplasms; Calmodulin; Cell Cycle; Cell Division; Drug Resistance; Flow Cytometry; Humans; Pi | 1992 |