Compounds > n-(3-iodopropen-1-yl)-2-carbomethoxy-3-(4-chlorophenyl)tropane

n-(3-iodopropen-1-yl)-2-carbomethoxy-3-(4-chlorophenyl)tropane and Restless-Legs-Syndrome

n-(3-iodopropen-1-yl)-2-carbomethoxy-3-(4-chlorophenyl)tropane has been researched along with Restless-Legs-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for n-(3-iodopropen-1-yl)-2-carbomethoxy-3-(4-chlorophenyl)tropane and Restless-Legs-Syndrome

Article	Year
Normal IPT and IBZM SPECT in drug-naive and levodopa-treated idiopathic restless legs syndrome. Neurology, 2001, Oct-09, Volume: 57, Issue:7 Fourteen drug-naive and 11 levodopa-treated patients with idiopathic restless legs syndrome (RLS), and 10 controls age-matched to each RLS group separately were examined with polysomnography (PSG), [(123)I]-(N)-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ((123)I-IPT) SPECT, and [(123)I]-(S)-2-hydroxy-3-iodo-6-methoxy-[(1-ethyl-2-pyrrolidinyl)methyl] benzamide ((123)I-IBZM) SPECT. Drug-naive and levodopa-treated patients with RLS and controls showed similar striatal dopamine transporter and dopamine D(2)-receptor binding, the latter declining with age. The authors conclude that striatal dopamine transporter and receptor density is normal in drug-naive and levodopa-treated patients with RLS. Topics: Aged; Benzamides; Dopamine Agents; Dopamine Antagonists; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Polysomnography; Pyrrolidines; Restless Legs Syndrome; Tomography, Emission-Computed, Single-Photon; Tropanes	2001

Article

Year

Normal IPT and IBZM SPECT in drug-naive and levodopa-treated idiopathic restless legs syndrome.

Neurology, 2001, Oct-09, Volume: 57, Issue:7

Fourteen drug-naive and 11 levodopa-treated patients with idiopathic restless legs syndrome (RLS), and 10 controls age-matched to each RLS group separately were examined with polysomnography (PSG), [(123)I]-(N)-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ((123)I-IPT) SPECT, and [(123)I]-(S)-2-hydroxy-3-iodo-6-methoxy-[(1-ethyl-2-pyrrolidinyl)methyl] benzamide ((123)I-IBZM) SPECT. Drug-naive and levodopa-treated patients with RLS and controls showed similar striatal dopamine transporter and dopamine D(2)-receptor binding, the latter declining with age. The authors conclude that striatal dopamine transporter and receptor density is normal in drug-naive and levodopa-treated patients with RLS.

Topics: Aged; Benzamides; Dopamine Agents; Dopamine Antagonists; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Polysomnography; Pyrrolidines; Restless Legs Syndrome; Tomography, Emission-Computed, Single-Photon; Tropanes

2001