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n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide and Lung Neoplasms

n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide has been researched along with Lung Neoplasms in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badawi, AM; Cecchi, A; Morsy, SM; Scozzafava, A; Supuran, CT1
Beijnen, JH; Dittrich, C; Huitema, AD; Schellens, JH; Wanders, J; Zandvliet, AS1
Bosquee, L; Cattell, E; Ellis, P; Huitema, AD; Johnston, C; Norbury, CJ; Reck, M; Talbot, DC; von Pawel, J; Yule, SM; Zandvliet, AS1
Fukumoto, H; Fukuoka, K; Iwamoto, Y; Nakamura, T; Narita, N; Nishio, K; Saijo, N; Usuda, J; Yoneda, T1

Trials

1 trial(s) available for n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide and Lung Neoplasms

ArticleYear
A randomized phase II pharmacokinetic and pharmacodynamic study of indisulam as second-line therapy in patients with advanced non-small cell lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Mar-15, Volume: 13, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Middle Aged; Sulfonamides; Survival Analysis; Treatment Outcome

2007

Other Studies

3 other study(ies) available for n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide and Lung Neoplasms

ArticleYear
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.
    Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; HCT116 Cells; Humans; Isoenzymes; Lung Neoplasms; Sulfonamides

2009
Population pharmacokinetic and pharmacodynamic analysis to support treatment optimization of combination chemotherapy with indisulam and carboplatin.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Sulfonamides; Thrombocytopenia; Treatment Outcome

2008
Mechanisms of action of the novel sulfonamide anticancer agent E7070 on cell cycle progression in human non-small cell lung cancer cells.
    Investigational new drugs, 2001, Volume: 19, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Lung Neoplasms; Phosphorylation; Retinoblastoma Protein; Sulfonamides; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001