n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Liver Dysfunction in 3 studies
N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although trauma-hemorrhage produces tissue hypoxia, systemic inflammatory response and organ dysfunction, the mechanisms responsible for these alterations are not clear." | 1.35 | Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury. ( Bland, KI; Chaudry, IH; Choudhry, MA; Hsu, JT; Kan, WH; Raju, R; Schwacha, MG, 2008) |
| " Nitric oxide can combine with superoxide to form peroxynitrite, a molecule that may participate in the toxic mechanisms of hepatotoxins, such as acetaminophen and bacterial endotoxin." | 1.31 | iNOS-null mice are not resistant to cadmium chloride-induced hepatotoxicity. ( Harstad, EB; Klaassen, CD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, TH | 1 |
| Liao, FT | 1 |
| Yang, YC | 1 |
| Wang, JJ | 1 |
| Kan, WH | 1 |
| Hsu, JT | 1 |
| Schwacha, MG | 1 |
| Choudhry, MA | 1 |
| Raju, R | 1 |
| Bland, KI | 1 |
| Chaudry, IH | 1 |
| Harstad, EB | 1 |
| Klaassen, CD | 1 |
3 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Liver Dysfunction
| Article | Year |
|---|---|
Inhibition of inducible nitric oxide synthesis ameliorates liver ischemia and reperfusion injury induced transient increase in arterial stiffness.
Topics: Amidines; Animals; Benzylamines; Biomarkers; Cytoprotection; Disease Models, Animal; Enzyme Inhibito | 2014 |
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
Topics: Amidines; Animals; Benzylamines; Blood Pressure; Chemokines; Cytokines; Disease Models, Animal; Enzy | 2008 |
iNOS-null mice are not resistant to cadmium chloride-induced hepatotoxicity.
Topics: Alanine Transaminase; Amidines; Animals; Benzylamines; Cadmium Chloride; Chemical and Drug Induced L | 2002 |