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n-(3-(aminomethyl)benzyl)acetamidine and Hypoxia

n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Hypoxia in 9 studies

N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"We employed isolated perfused and ventilated rabbit lungs to determine the influence of hypercapnia with or without acidosis (pH corrected with sodium bicarbonate), and inhibitors of endothelial as well as inducible NO synthase on acute or sustained HPV (180 min) and endothelial permeability."3.78Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction. ( Dehghani, GA; Egemnazarov, B; Ghofrani, HA; Grimminger, F; Ketabchi, F; Schermuly, RT; Seeger, W; Shid-Moosavi, SM; Sommer, N; Weissmann, N, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, AL1
Desai, RA1
Bloomfield, PS1
McIntosh, PR1
Chapple, KJ1
Linington, C1
Fairless, R1
Diem, R1
Kasti, M1
Murphy, MP1
Smith, KJ1
Diesen, DL1
Hess, DT1
Stamler, JS1
Murugan, M1
Sivakumar, V1
Lu, J1
Ling, EA1
Kaur, C1
Vaughan, DJ1
Brogan, TV1
Kerr, ME1
Deem, S1
Luchtel, DL1
Swenson, ER1
Jiang, H1
Koubi, D1
Zhang, L1
Kuo, J1
Rodriguez, AI1
Hunter, TJ1
Gautam, SC1
Levine, RA1
Shi, Q1
Liu, X1
Wang, N1
Zheng, X1
Ran, J1
Liu, Z1
Fu, J1
Zheng, J1
Rus, A1
Castro, L1
Del Moral, ML1
Peinado, A1
Ketabchi, F1
Ghofrani, HA1
Schermuly, RT1
Seeger, W1
Grimminger, F1
Egemnazarov, B1
Shid-Moosavi, SM1
Dehghani, GA1
Weissmann, N1
Sommer, N1
Song, MY1
Zwemer, CF1
Whitesall, SE1
D'Alecy, LG1

Trials

1 trial available for n-(3-(aminomethyl)benzyl)acetamidine and Hypoxia

ArticleYear
Neurological deficits caused by tissue hypoxia in neuroinflammatory disease.
    Annals of neurology, 2013, Volume: 74, Issue:6

    Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental

2013

Other Studies

8 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Hypoxia

ArticleYear
Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal.
    Circulation research, 2008, Aug-29, Volume: 103, Issue:5

    Topics: Amidines; Animals; Aorta; Benzylamines; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Hemo

2008
Expression of N-methyl D-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF-κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats.
    Glia, 2011, Volume: 59, Issue:4

    Topics: Amidines; Animals; Animals, Newborn; Benzylamines; Blotting, Western; Calcium; Cell Death; Cells, Cu

2011
Contributions of nitric oxide synthase isozymes to exhaled nitric oxide and hypoxic pulmonary vasoconstriction in rabbit lungs.
    American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 284, Issue:5

    Topics: Acetylcholine; Amidines; Animals; Benzylamines; Breath Tests; Hypoxia; Immunohistochemistry; Indazol

2003
Inhibitors of iNOS protects PC12 cells against the apoptosis induced by oxygen and glucose deprivation.
    Neuroscience letters, 2005, Feb-25, Volume: 375, Issue:1

    Topics: Amidines; Animals; Apoptosis; Benzylamines; Blotting, Western; Caspase 3; Caspases; Cytochromes c; D

2005
1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia.
    Behavioural brain research, 2017, 02-15, Volume: 319

    Topics: Animals; Annexin A5; Apoptosis; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Gene E

2017
Inducible NOS inhibitor 1400W reduces hypoxia/re-oxygenation injury in rat lung.
    Redox report : communications in free radical research, 2010, Volume: 15, Issue:4

    Topics: Animals; Hypoxia; Imines; Lung; Lung Injury; Male; Nitric Oxide Synthase Type II; Oxygen; Rats; Rats

2010
Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction.
    Respiratory research, 2012, Jan-31, Volume: 13

    Topics: Acidosis; Animals; Enzyme Inhibitors; Hypercapnia; Hypoxia; Imines; Lung; Male; Nitric Oxide Synthas

2012
Acute and conditioned hypoxic tolerance augmented by endothelial nitric oxide synthase inhibition in mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:2

    Topics: Acute Disease; Animals; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; Imines; Indazol

2007