n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Cardiomegaly in 3 studies
N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rat aortic banding model of cardiac hypertrophy was used to test the hypothesis that reversible inhibition of mitochondrial respiration by nitric oxide (NO*) elicits a bioenergetic defect in the hypertrophied heart." | 1.31 | Bioenergetics in cardiac hypertrophy: mitochondrial respiration as a pathological target of NO*. ( Anderson, PG; Brookes, PS; Dai, L; Darley-Usmar, VM, 2001) |
| "ACF induced cardiac hypertrophy in rats with compensated (36%) and decompensated (76%) HF." | 1.31 | Role of myocardial inducible nitric oxide synthase in contractile dysfunction and beta-adrenergic hyporesponsiveness in rats with experimental volume-overload heart failure. ( Abassi, Z; Binah, O; Gealekman, O; Rubinstein, I; Winaver, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, P | 1 |
| Xu, X | 1 |
| Hu, X | 1 |
| van Deel, ED | 1 |
| Zhu, G | 1 |
| Chen, Y | 1 |
| Dai, L | 1 |
| Brookes, PS | 1 |
| Darley-Usmar, VM | 1 |
| Anderson, PG | 1 |
| Gealekman, O | 1 |
| Abassi, Z | 1 |
| Rubinstein, I | 1 |
| Winaver, J | 1 |
| Binah, O | 1 |
3 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Cardiomegaly
| Article | Year |
|---|---|
Inducible nitric oxide synthase deficiency protects the heart from systolic overload-induced ventricular hypertrophy and congestive heart failure.
Topics: Amidines; Animals; Aortic Diseases; Atrial Natriuretic Factor; Benzylamines; Cardiomegaly; Chronic D | 2007 |
Bioenergetics in cardiac hypertrophy: mitochondrial respiration as a pathological target of NO*.
Topics: Amidines; Animals; Benzylamines; Cardiomegaly; Cell Respiration; Energy Metabolism; Enzyme Inhibitor | 2001 |
Role of myocardial inducible nitric oxide synthase in contractile dysfunction and beta-adrenergic hyporesponsiveness in rats with experimental volume-overload heart failure.
Topics: Adrenergic beta-Agonists; Amidines; Animals; Arteriovenous Fistula; Benzylamines; Calcium; Cardiac V | 2002 |