n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Bronchial Hyperreactivity in 4 studies
N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koarai, A | 1 |
| Ichinose, M | 1 |
| Sugiura, H | 1 |
| Yamagata, S | 1 |
| Hattori, T | 1 |
| Shirato, K | 1 |
| Muijsers, RB | 1 |
| van Ark, I | 1 |
| Folkerts, G | 1 |
| Koster, AS | 1 |
| van Oosterhout, AJ | 1 |
| Postma, DS | 1 |
| Nijkamp, FP | 1 |
| Que, LG | 1 |
| Liu, L | 1 |
| Yan, Y | 1 |
| Whitehead, GS | 1 |
| Gavett, SH | 1 |
| Schwartz, DA | 1 |
| Stamler, JS | 1 |
| Komlósi, ZI | 1 |
| Pozsonyi, E | 1 |
| Tábi, T | 1 |
| Szöko, E | 1 |
| Nagy, A | 1 |
| Bartos, B | 1 |
| Kozma, GT | 1 |
| Tamási, L | 1 |
| Orosz, M | 1 |
| Magyar, P | 1 |
| Losonczy, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge[NCT03926741] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2019-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Allergic airway hyperresponsiveness and eosinophil infiltration is reduced by a selective iNOS inhibitor, 1400W, in mice.
Topics: Amidines; Animals; Benzylamines; Blotting, Western; Bronchial Hyperreactivity; Enzyme Inhibitors; Eo | 2000 |
Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice.
Topics: Acetophenones; Amidines; Animals; Antioxidants; Benzylamines; Bronchial Hyperreactivity; Bronchoalve | 2001 |
Protection from experimental asthma by an endogenous bronchodilator.
Topics: Adrenergic beta-Agonists; Alcohol Dehydrogenase; Allergens; Animals; Asthma; Bronchi; Bronchial Hype | 2005 |
Lipopolysaccharide exposure makes allergic airway inflammation and hyper-responsiveness less responsive to dexamethasone and inhibition of iNOS.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Dexamethasone; Drug Resistance; Female; Gluco | 2006 |