n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Asthma in 5 studies
N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we examined the role of NO in lipopolysaccharide (LPS)-induced inflammation in an ovalbumin (OVA)-challenged mouse asthma model." | 3.81 | Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90. ( Chiang, CP; Huang, CF; Lee, MY; Liu, HY; Sun, GH; Sun, KH; Tang, SJ; Tsou, YC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prado, CM | 1 |
| Yano, L | 1 |
| Rocha, G | 1 |
| Starling, CM | 1 |
| Capelozzi, VL | 1 |
| Leick-Maldonado, EA | 1 |
| Martins, Mde A | 1 |
| Tibério, IF | 1 |
| Lee, MY | 1 |
| Sun, KH | 1 |
| Chiang, CP | 1 |
| Huang, CF | 1 |
| Sun, GH | 1 |
| Tsou, YC | 1 |
| Liu, HY | 1 |
| Tang, SJ | 1 |
| Shin, TS | 1 |
| Lee, BJ | 1 |
| Tae, YM | 1 |
| Kim, YS | 1 |
| Jeon, SG | 1 |
| Gho, YS | 1 |
| Choi, DC | 1 |
| Kim, YK | 1 |
| Que, LG | 1 |
| Liu, L | 1 |
| Yan, Y | 1 |
| Whitehead, GS | 1 |
| Gavett, SH | 1 |
| Schwartz, DA | 1 |
| Stamler, JS | 1 |
| Komlósi, ZI | 1 |
| Pozsonyi, E | 1 |
| Tábi, T | 1 |
| Szöko, E | 1 |
| Nagy, A | 1 |
| Bartos, B | 1 |
| Kozma, GT | 1 |
| Tamási, L | 1 |
| Orosz, M | 1 |
| Magyar, P | 1 |
| Losonczy, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge[NCT03926741] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2019-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Asthma
| Article | Year |
|---|---|
Effects of inducible nitric oxide synthase inhibition in bronchial vascular remodeling-induced by chronic allergic pulmonary inflammation.
Topics: Administration, Inhalation; Amidines; Animals; Asthma; Benzylamines; Blood Vessels; Bronchi; Collage | 2011 |
Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90.
Topics: Animals; Asthma; Cells, Cultured; Cytokines; Disease Models, Animal; Female; HSP90 Heat-Shock Protei | 2015 |
Role of inducible nitric oxide synthase on the development of virus-associated asthma exacerbation which is dependent on Th1 and Th17 cell responses.
Topics: Animals; Asthma; Imines; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide Synt | 2010 |
Protection from experimental asthma by an endogenous bronchodilator.
Topics: Adrenergic beta-Agonists; Alcohol Dehydrogenase; Allergens; Animals; Asthma; Bronchi; Bronchial Hype | 2005 |
Lipopolysaccharide exposure makes allergic airway inflammation and hyper-responsiveness less responsive to dexamethasone and inhibition of iNOS.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Dexamethasone; Drug Resistance; Female; Gluco | 2006 |