n-(3-(aminomethyl)benzyl)acetamidine has been researched along with Alloxan Diabetes in 9 studies
N-(3-(aminomethyl)benzyl)acetamidine: structure in first source
N-[3-(aminomethyl)benzyl]acetamidine : An aralkylamine that is Nbenzylacetamidine substituted at position 3 on the benzene ring by an aminomethyl group. An inhibitor of nitric oxide synthase.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study demonstrated that iNOS-derived superoxide generation was reduced, and that the NO bioavailability was increased, by treatment with the NOS-cofactor, tetrahydrobiopterin (BH4), before I/R in the hearts isolated from diabetic rats." | 1.37 | Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart. ( Fujita, M; Ito, S; Iwasaka, T; Katano, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K, 2011) |
| " In conclusion, while NO bioavailability in mTALs is reduced during diabetes, free radical scavenging with tempol unmasks increased NO production that involves PP2B-dependent activation of NOS1 and NOS2." | 1.35 | PP2B-dependent NO production in the medullary thick ascending limb during diabetes. ( Carmines, PK; Foster, JM; Pollock, JS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foster, JM | 1 |
| Carmines, PK | 1 |
| Pollock, JS | 1 |
| Rydgren, T | 1 |
| Sandler, S | 1 |
| Cheng, X | 2 |
| Pang, CC | 2 |
| Cheng, XS | 1 |
| Kuo, KH | 1 |
| Nagareddy, PR | 1 |
| Xia, Z | 1 |
| McNeill, JH | 1 |
| MacLeod, KM | 1 |
| Rodriguez, AI | 1 |
| Pereira-Flores, K | 1 |
| Hernández-Salinas, R | 1 |
| Boric, MP | 1 |
| Velarde, V | 1 |
| Okazaki, T | 1 |
| Otani, H | 1 |
| Shimazu, T | 1 |
| Yoshioka, K | 1 |
| Fujita, M | 1 |
| Katano, T | 1 |
| Ito, S | 1 |
| Iwasaka, T | 1 |
| Liu, Y | 1 |
| Qu, Y | 1 |
| Wang, R | 1 |
| Ma, Y | 1 |
| Xia, C | 1 |
| Gao, C | 1 |
| Liu, J | 2 |
| Lian, K | 1 |
| Xu, A | 1 |
| Lu, X | 1 |
| Sun, L | 1 |
| Yang, L | 1 |
| Lau, WB | 1 |
| Gao, E | 1 |
| Koch, W | 1 |
| Wang, H | 1 |
| Tao, L | 1 |
| Wang, X | 1 |
| Tan, Y | 1 |
| Xu, B | 1 |
| Lu, L | 1 |
| Zhao, M | 1 |
| Ma, J | 1 |
| Liang, H | 1 |
| Yu, S | 1 |
9 other studies available for n-(3-(aminomethyl)benzyl)acetamidine and Alloxan Diabetes
| Article | Year |
|---|---|
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.
Topics: Amidines; Animals; Benzylamines; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclic N-Oxides | 2009 |
Efficacy of 1400 W, a novel inhibitor of inducible nitric oxide synthase, in preventing interleukin-1beta-induced suppression of pancreatic islet function in vitro and multiple low-dose streptozotocin-induced diabetes in vivo.
Topics: Amidines; Animals; Benzylamines; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; En | 2002 |
Increased vasoconstriction to noradrenaline by 1400W, inhibitor of iNOS, in rats with streptozotocin-induced diabetes.
Topics: Amidines; Animals; Benzylamines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; | 2004 |
Inhibition of iNOS augments cardiovascular action of noradrenaline in streptozotocin-induced diabetes.
Topics: Acute Disease; Adrenergic beta-Antagonists; Amidines; Animals; Benzylamines; Blood Pressure; Depress | 2004 |
Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes.
Topics: Amidines; Angiotensin II; Animals; Benzylamines; Blood Pressure; Blotting, Western; Diabetes Mellitu | 2005 |
High glucose increases B1-kinin receptor expression and signaling in endothelial cells.
Topics: Amidines; Animals; Benzylamines; Bradykinin; Diabetes Mellitus, Experimental; Endothelial Cells; Enz | 2006 |
Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart.
Topics: Animals; Biopterins; Cyclic GMP; Diabetes Complications; Diabetes Mellitus, Experimental; Dithiothre | 2011 |
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; | 2012 |
GPR30 Attenuates Myocardial Fibrosis in Diabetic Ovariectomized Female Rats: Role of iNOS Signaling.
Topics: Amidines; Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Di | 2018 |