n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Stomach Neoplasms in 17 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Stomach Neoplasms: Tumors or cancer of the STOMACH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Periostin mRNA in gastric cancer cells was silenced using small interfering RNA (siRNA) techniques and periostin gene expression was evaluated by quantitative reverse transcription-polymerase chain reaction." | 1.37 | Enhanced proliferation, invasion, and epithelial-mesenchymal transition of nicotine-promoted gastric cancer by periostin. ( Liu, BA; Liu, Y, 2011) |
| "In a gastric cancer cell line with a very low 15-PGDH expression (TMK-1), the 15-PGDH promoter was methylated and treatment with a demethylating agent 5-aza-2'-deoxycytidine restored 15-PGDH expression." | 1.35 | 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. ( Ganesan, A; Haglund, C; Hemmes, A; Junnila, S; Kokkola, A; Monni, O; Mrena, J; Nykänen, A; Petrova, TV; Ristimäki, A; Tai, HH; Thiel, A, 2009) |
| "Treatment with proglumide and NS-398 significantly reduced the bcl-2 mRNA and protein expression in the MKN-45 cells (P < 0." | 1.33 | [Effects of gastrin receptor antagonist and cyclooxygenase-2 inhibitor on proliferation and apoptosis of gastric cancer cell]. ( Cheng, YL; Ding, GX; Shao, Y; Su, H; Sun, WH; Xu, HC; Xue, YP; Zhang, LJ; Zhang, T, 2006) |
| "MKN45 gastric cancer cells (5 x 10(6) cells/animal) that overexpress COX-2 were inoculated subcutaneously into athymic mice." | 1.30 | Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. ( Gunawan, ES; Hori, M; Kawano, S; Nagano, K; Sawaoka, H; Takei, Y; Tsuji, S; Tsujii, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| El-Obeid, A | 1 |
| Maashi, Y | 1 |
| AlRoshody, R | 1 |
| Alatar, G | 1 |
| Aljudayi, M | 1 |
| Al-Eidi, H | 1 |
| AlGaith, N | 1 |
| Khan, AH | 1 |
| Hassib, A | 1 |
| Matou-Nasri, S | 1 |
| Li, H | 1 |
| Zhang, X | 1 |
| Feng, L | 1 |
| Thiel, A | 1 |
| Ganesan, A | 1 |
| Mrena, J | 1 |
| Junnila, S | 1 |
| Nykänen, A | 1 |
| Hemmes, A | 1 |
| Tai, HH | 1 |
| Monni, O | 1 |
| Kokkola, A | 1 |
| Haglund, C | 1 |
| Petrova, TV | 1 |
| Ristimäki, A | 1 |
| Liu, Y | 1 |
| Liu, BA | 1 |
| Targosz, A | 1 |
| Brzozowski, T | 1 |
| Pierzchalski, P | 1 |
| Szczyrk, U | 1 |
| Ptak-Belowska, A | 1 |
| Konturek, SJ | 1 |
| Pawlik, W | 1 |
| Gu, KS | 1 |
| Chen, Y | 1 |
| Honjo, S | 2 |
| Kase, S | 1 |
| Osaki, M | 2 |
| Ardyanto, TD | 2 |
| Kaibara, N | 1 |
| Ito, H | 2 |
| Hiramatsu, T | 1 |
| Maeta, N | 1 |
| Huang, SP | 1 |
| Wu, MS | 1 |
| Shun, CT | 1 |
| Wang, HP | 1 |
| Hsieh, CY | 1 |
| Kuo, ML | 1 |
| Lin, JT | 1 |
| Fu, YG | 1 |
| Sung, JJ | 1 |
| Wu, KC | 1 |
| Wu, HP | 1 |
| Yu, J | 1 |
| Chan, M | 1 |
| Chan, VY | 1 |
| Chan, KK | 1 |
| Fan, DM | 1 |
| Leung, WK | 1 |
| Sun, WH | 1 |
| Su, H | 1 |
| Zhang, LJ | 1 |
| Shao, Y | 1 |
| Xu, HC | 1 |
| Zhang, T | 1 |
| Xue, YP | 1 |
| Ding, GX | 1 |
| Cheng, YL | 1 |
| Takehara, H | 1 |
| Iwamoto, J | 2 |
| Mizokami, Y | 1 |
| Takahashi, K | 1 |
| Ootubo, T | 1 |
| Miura, S | 1 |
| Narasaka, T | 1 |
| Takeyama, H | 1 |
| Omata, T | 1 |
| Shimokobe, K | 1 |
| Ito, M | 1 |
| Matsuoka, T | 1 |
| Tsuji, S | 3 |
| Kawano, S | 3 |
| Sawaoka, H | 3 |
| Takei, Y | 2 |
| Kobayashi, I | 1 |
| Nagano, K | 2 |
| Fusamoto, H | 1 |
| Kamada, T | 1 |
| Tsujii, M | 2 |
| Gunawan, ES | 1 |
| Hori, M | 2 |
| Murata, H | 1 |
| Lim, JW | 1 |
| Kim, H | 1 |
| Kim, KH | 1 |
| Husain, SS | 1 |
| Szabo, IL | 1 |
| Pai, R | 1 |
| Soreghan, B | 1 |
| Jones, MK | 1 |
| Tarnawski, AS | 1 |
17 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Stomach Neoplasms
| Article | Year |
|---|---|
Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS.
Topics: Animals; Cyclooxygenase 2; Dinoprostone; Humans; Interleukin-6; Melanins; Mucin-4; Rats; Stomach Neo | 2023 |
Ghrelin Regulates Cyclooxygenase-2 Expression and Promotes Gastric Cancer Cell Progression.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Computational Biology; Cyclooxygenase 2; Cyclooxygenase | 2021 |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; Cyclooxygenase 2; Cyclooxygenase Inh | 2009 |
Enhanced proliferation, invasion, and epithelial-mesenchymal transition of nicotine-promoted gastric cancer by periostin.
Topics: Animals; Apoptosis; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cyclooxygenas | 2011 |
Helicobacter pylori promotes apoptosis, activates cyclooxygenase (COX)-2 and inhibits heat shock protein HSP70 in gastric cancer epithelial cells.
Topics: Antigens, Bacterial; Apoptosis; Bacterial Proteins; bcl-2-Associated X Protein; Cell Line, Tumor; Cy | 2012 |
Mechanism of P-glycoprotein expression in the SGC7901 human gastric adenocarcinoma cell line induced by cyclooxygenase-2.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; A | 2012 |
COX-2 correlates with F-box protein, Skp2 expression and prognosis in human gastric carcinoma.
Topics: Apoptosis; Blotting, Western; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Surv | 2005 |
COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines.
Topics: Antibodies; Antineoplastic Agents; Apoptosis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloox | 2005 |
Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma.
Topics: Adult; Aged; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibit | 2005 |
Inhibition of gastric cancer-associated angiogenesis by antisense COX-2 transfectants.
Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA, Antisense; DNA, Compl | 2005 |
[Effects of gastrin receptor antagonist and cyclooxygenase-2 inhibitor on proliferation and apoptosis of gastric cancer cell].
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2 | 2006 |
Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells.
Topics: Adenocarcinoma; Arachidonic Acid; Biphenyl Compounds; Cell Line, Tumor; Cyclic AMP; Cyclooxygenase 2 | 2006 |
Evidences for involvement of cyclooxygenase-2 in proliferation of two gastrointestinal cancer cell lines.
Topics: Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 In | 1996 |
Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Cyclooxygenase Inhibitors; Dinoprostone; Female; H | 1998 |
Effects of NSAIDs on proliferation of gastric cancer cells in vitro: possible implication of cyclooxygenase-2 in cancer development.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Northern; Blotting, We | 1998 |
Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells.
Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhi | 2001 |
MAPK (ERK2) kinase--a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cyclooxygenase In | 2001 |