n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Reperfusion Injury in 12 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is known that cerebral ischemia can cause brain inflammation and adiposome can serve as a depot of inflammatory mediators." | 1.51 | Microglia-Derived Adiposomes are Potential Targets for the Treatment of Ischemic Stroke. ( Chang, YJ; Hsu, SL; Hsueh, CM; Liao, LY; Lin, CH; Tung, CW; Yang, TY, 2019) |
| "We investigated the role of COX-2 in lung injury induced by skeletal muscle ischemia reperfusion in rats and evaluated the effects of NS-398, a specific COX-2 inhibitor." | 1.43 | COX-2 inhibition attenuates lung injury induced by skeletal muscle ischemia reperfusion in rats. ( Jin, L; Lin, L; Miao, J; Shan, Y; Wang, L; Xiong, X; Ye, Y; Zhao, X; Zhuo, Q, 2016) |
| "After the anoxia treatment, each group was reoxygenated in a mixture of 95% air and 5% CO2 incubator for 6 h." | 1.34 | Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells. ( Han, BS; Huang, JH; Shi, LB, 2007) |
| "Pretreatment with indomethacin completely reversed both of the therapeutic effects of dalteparin, whereas pretreatment with NS-398, a selective inhibitor of cyclooxygenase-2, did not." | 1.33 | Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats. ( Harada, N; Okajima, K; Uchiba, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Liu, P | 1 |
| Hu, M | 1 |
| Lu, S | 1 |
| Lyu, Z | 1 |
| Kou, Y | 1 |
| Sun, Y | 1 |
| Zhao, X | 2 |
| Liu, F | 1 |
| Tian, J | 1 |
| Lin, CH | 1 |
| Liao, LY | 1 |
| Yang, TY | 1 |
| Chang, YJ | 1 |
| Tung, CW | 1 |
| Hsu, SL | 1 |
| Hsueh, CM | 1 |
| Wang, L | 1 |
| Shan, Y | 1 |
| Ye, Y | 1 |
| Jin, L | 1 |
| Zhuo, Q | 1 |
| Xiong, X | 1 |
| Lin, L | 1 |
| Miao, J | 1 |
| Zhang, J | 1 |
| Barasch, N | 1 |
| Li, RC | 1 |
| Sapirstein, A | 1 |
| Hiratsuka, T | 1 |
| Futagami, S | 1 |
| Tatsuguchi, A | 1 |
| Suzuki, K | 1 |
| Shinji, Y | 1 |
| Kusunoki, M | 1 |
| Shinoki, K | 1 |
| Nishigaki, H | 1 |
| Fujimori, S | 1 |
| Wada, K | 1 |
| Miyake, K | 1 |
| Gudis, K | 1 |
| Tsukui, T | 1 |
| Sakamoto, C | 1 |
| Sato, N | 1 |
| Kozar, RA | 1 |
| Zou, L | 1 |
| Weatherall, JM | 1 |
| Attuwaybi, B | 1 |
| Moore-Olufemi, SD | 1 |
| Weisbrodt, NW | 1 |
| Moore, FA | 1 |
| Harada, N | 2 |
| Okajima, K | 2 |
| Uchiba, M | 2 |
| Shi, LB | 1 |
| Huang, JH | 1 |
| Han, BS | 1 |
| Birkenmeier, K | 1 |
| Staudt, A | 1 |
| Schunck, WH | 1 |
| Janke, I | 1 |
| Labitzke, C | 1 |
| Prange, T | 1 |
| Trimpert, C | 1 |
| Krieg, T | 1 |
| Landsberger, M | 1 |
| Stangl, V | 1 |
| Felix, SB | 1 |
| Maricic, N | 1 |
| Ehrlich, K | 1 |
| Gretzer, B | 1 |
| Schuligoi, R | 1 |
| Respondek, M | 1 |
| Peskar, BM | 1 |
| Brzozowski, T | 1 |
| Konturek, PC | 1 |
| Konturek, SJ | 1 |
| Sliwowski, Z | 1 |
| Drozdowicz, D | 1 |
| Stachura, J | 1 |
| Pajdo, R | 1 |
| Hahn, EG | 1 |
| Katsuragi, T | 1 |
12 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Reperfusion Injury
| Article | Year |
|---|---|
Naoxintong restores ischemia injury and inhibits thrombosis via COX2-VEGF/ NFκB signaling.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease M | 2021 |
Microglia-Derived Adiposomes are Potential Targets for the Treatment of Ischemic Stroke.
Topics: Anilides; Animals; Animals, Newborn; Brain Ischemia; Cell Death; Culture Media, Serum-Free; Cyclooxy | 2019 |
COX-2 inhibition attenuates lung injury induced by skeletal muscle ischemia reperfusion in rats.
Topics: Animals; Aquaporin 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Interleukin-1beta; Lung; Lung I | 2016 |
Inhibition of cytosolic phospholipase A(2) alpha protects against focal ischemic brain damage in mice.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Body Temp | 2012 |
COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice.
Topics: Alanine; Animals; Blotting, Western; Celiac Artery; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygena | 2005 |
Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyg | 2005 |
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anticoagulants; Calcium; Cyclooxygenase 2 Inhibitors; Daltepa | 2006 |
Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells.
Topics: Cell Line; Cell Survival; Cold Temperature; Endothelium, Vascular; Gene Expression Regulation; Human | 2007 |
COX-2-dependent and potentially cardioprotective effects of negative inotropic substances released after ischemia.
Topics: Adenosine Triphosphate; Animals; Calcium Signaling; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenas | 2007 |
Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 1999 |
Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 1999 |
Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; | 2002 |