n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Pregnancy in 18 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arachidonic acid (AA) release was measured in tritiated AA-loaded myometrial cells." | 1.31 | Oxytocin signaling in human myometrium is impaired by prolonged exposure to interleukin-1. ( Chiao, JP; Rauk, PN, 2000) |
| "Indomethacin was more effective than NS-398, except for their actions on PGF(2 alpha)production by the day 29 placenta where indomethacin and NS-398 were equiactive." | 1.31 | Effects of indomethacin, NS-398 (a selective prostaglandin H synthase-2 inhibitor) and protein synthesis inhibitors on prostaglandin production by the guinea-pig placenta. ( Aitken, H; Poyser, NL, 2001) |
| "Preeclampsia is associated with altered biosynthesis of vasoactive prostanoids in placental villi." | 1.30 | The expression and activity of prostaglandin H synthase-2 is enhanced in trophoblast from women with preeclampsia. ( Anteby, EY; Graham, C; Huang, X; Johnson, RD; Nelson, DM; Polakoski, KL; Sadovsky, Y, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Osikoya, O | 1 |
| Cushen, SC | 1 |
| Ricci, CA | 1 |
| Goulopoulou, S | 1 |
| Ramos-Alves, FE | 1 |
| de Queiroz, DB | 1 |
| Santos-Rocha, J | 1 |
| Duarte, GP | 1 |
| Xavier, FE | 1 |
| Mijovic, JE | 1 |
| Zakar, T | 1 |
| Zaragoza, DB | 1 |
| Olson, DM | 1 |
| Mertz, HL | 1 |
| Liu, J | 1 |
| Valego, NK | 1 |
| Stallings, SP | 1 |
| Figueroa, JP | 1 |
| Rose, JC | 1 |
| Huang, JC | 1 |
| Goldsby, JS | 1 |
| Arbab, F | 1 |
| Melhem, Z | 1 |
| Aleksic, N | 1 |
| Wu, KK | 1 |
| Vaughan, JE | 1 |
| Walsh, SW | 1 |
| Ford, GD | 1 |
| Pérez Martínez, S | 1 |
| Hermoso, M | 1 |
| Farina, M | 2 |
| Ribeiro, ML | 2 |
| Rapanelli, M | 1 |
| Espinosa, M | 1 |
| Villalón, M | 1 |
| Franchi, A | 1 |
| Mitchell, MD | 1 |
| Sato, TA | 1 |
| Wang, A | 1 |
| Keelan, JA | 1 |
| Ponnampalam, AP | 1 |
| Glass, M | 1 |
| Ishihara, O | 2 |
| Numari, H | 2 |
| Saitoh, M | 2 |
| Arai, Y | 2 |
| Takanashi, H | 2 |
| Kitagawa, H | 2 |
| Kinoshita, K | 2 |
| Johnson, RD | 1 |
| Sadovsky, Y | 2 |
| Graham, C | 1 |
| Anteby, EY | 1 |
| Polakoski, KL | 1 |
| Huang, X | 1 |
| Nelson, DM | 2 |
| Poyser, NL | 2 |
| Muglia, LJ | 1 |
| Gross, GA | 1 |
| Harris, KC | 1 |
| Koki, A | 1 |
| Masferrer, JL | 1 |
| Olson, LM | 1 |
| Takahashi, Y | 1 |
| Roman, C | 1 |
| Chemtob, S | 1 |
| Tse, MM | 1 |
| Lin, E | 1 |
| Heymann, MA | 1 |
| Clyman, RI | 1 |
| Ogando, D | 1 |
| Gimeno, M | 1 |
| Franchi, AM | 1 |
| Rauk, PN | 1 |
| Chiao, JP | 1 |
| Aitken, H | 1 |
| Malek, A | 1 |
| Sager, R | 1 |
| Schneider, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing In Vitro Fertilization (IVF)[NCT02591186] | 60 participants (Actual) | Interventional | 2015-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Pregnancy
| Article | Year |
|---|---|
Cyclooxygenase-dependent mechanisms mediate in part the anti-dilatory effects of perivascular adipose tissue in uterine arteries from pregnant rats.
Topics: Acetylcholine; Adipose Tissue; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitor | 2021 |
Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Dinoprost; Endothelial | 2012 |
Tyrphostins inhibit lipopolysaccharide induced preterm labor in mice.
Topics: Animals; Disease Models, Animal; Female; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitrobenzen | 2002 |
Inhibition of cyclooxygenase-2: effects on renin secretion and expression in fetal lambs.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cells, Cultured; | 2003 |
Oviduct prostacyclin functions as a paracrine factor to augment the development of embryos.
Topics: Animals; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase | 2004 |
Thromboxane mediates neutrophil superoxide production in pregnancy.
Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; H | 2006 |
17-beta-Estradiol upregulates COX-2 in the rat oviduct.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epithelium; Estradiol; Est | 2006 |
Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism.
Topics: Adult; Amnion; Blotting, Western; Cannabinoid Receptor Modulators; Chorion; Cyclohexanols; Cyclooxyg | 2008 |
Prostaglandin E2 production by endogenous secretion of interleukin-1 in decidual cells obtained before and after the labor.
Topics: Blotting, Western; Cesarean Section; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase I | 1996 |
The expression and activity of prostaglandin H synthase-2 is enhanced in trophoblast from women with preeclampsia.
Topics: Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclooxygenase Inhibitors; Female; Fluoresce | 1997 |
Prostaglandin E2 production by endogenous secretion of interleukin-1 in decidual cells from term fetal membrane.
Topics: Cesarean Section; Cyclooxygenase Inhibitors; Decidua; Delivery, Obstetric; Dinoprostone; Female; Hum | 1997 |
A comparison of the effects of indomethacin and NS-398 (a selective prostaglandin H synthase-2 inhibitor) on implantation in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase | 1999 |
Effective diminution of amniotic prostaglandin production by selective inhibitors of cyclooxygenase type 2.
Topics: Amnion; Blotting, Western; Chorion; Cyclooxygenase Inhibitors; Decidua; Dinoprostone; Electrophoresi | 2000 |
Cyclooxygenase-2 inhibitors constrict the fetal lamb ductus arteriosus both in vitro and in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase | 2000 |
IL1alpha augments prostaglandin synthesis in pregnant rat uteri by a nitric oxide mediated mechanism.
Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Femal | 2000 |
Oxytocin signaling in human myometrium is impaired by prolonged exposure to interleukin-1.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Calcimycin; Calcium; Cells, Cultured; Cyclooxygenase | 2000 |
Effects of indomethacin, NS-398 (a selective prostaglandin H synthase-2 inhibitor) and protein synthesis inhibitors on prostaglandin production by the guinea-pig placenta.
Topics: Animals; Cell Culture Techniques; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Indomethacin; Isoe | 2001 |
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants.
Topics: Adult; Cell Hypoxia; Chorionic Villi; Culture Techniques; Cyclooxygenase Inhibitors; Cytokines; Drug | 2001 |