n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Pleurisy in 7 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, using rat carrageenin-induced pleurisy, we found that treatment of rats with either indomethacin or NS-398 suppressed the pleurisy at 2 h but significantly exacerbated this reaction at 48 h." | 3.71 | Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. ( Di Rosa, M; Ialenti, A; Ianaro, A; Maffia, P; Pisano, B, 2001) |
| "In rat carrageenin-induced pleurisy, the plasma exudation rate peaked at 5 h, at which time COX-2 was detectable in cells from the pleural exudate." | 1.30 | Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1. ( Harada, Y; Hatanaka, K; Katori, M; Kawamura, M; Ogino, K, 1997) |
| " NS-398 and nimesulide dosing did not reduce thromboxane B2 production from platelets isolated from rats with carrageenin-induced pleurisy, demonstrating that at the doses used, cyclooxygenase 2 inhibitors did not inhibit cyclooxygenase 1, as platelets contain only this isoform." | 1.30 | Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. ( Gilroy, DW; Tomlinson, A; Willoughby, DA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colville-Nash, PR | 1 |
| Gilroy, DW | 2 |
| Willis, D | 1 |
| Paul-Clark, MJ | 1 |
| Moore, AR | 1 |
| Willoughby, DA | 2 |
| Katori, M | 2 |
| Harada, Y | 4 |
| Hatanaka, K | 4 |
| Majima, M | 1 |
| Kawamura, M | 4 |
| Ohno, T | 3 |
| Aizawa, A | 1 |
| Yamamoto, S | 1 |
| Ogino, K | 3 |
| Saito, M | 1 |
| Ogino, M | 1 |
| Yang, Q | 1 |
| Tomlinson, A | 1 |
| Ianaro, A | 1 |
| Ialenti, A | 1 |
| Maffia, P | 1 |
| Pisano, B | 1 |
| Di Rosa, M | 1 |
7 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Pleurisy
| Article | Year |
|---|---|
Prostaglandin F2alpha produced by inducible cyclooxygenase may contribute to the resolution of inflammation.
Topics: Analysis of Variance; Animals; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Inflammation; | 2005 |
Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor.
Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Dexamethasone; Enzyme Induction; Isoenzyme | 1995 |
Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase | 1997 |
Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygen | 1998 |
Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo | 1998 |
Meloxicam inhibits prostaglandin E(2) generation via cyclooxygenase 2 in the inflammatory site but not that via cyclooxygenase 1 in the stomach.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cycloox | 2000 |
Role of cyclopentenone prostaglandins in rat carrageenin pleurisy.
Topics: Active Transport, Cell Nucleus; Animals; Carrageenan; Cyclooxygenase Inhibitors; Disease Models, Ani | 2001 |