n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Ovarian Neoplasms in 14 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "VEGF may play a role in ovarian cancer progression in the hen and the proliferation of ascites cells can be decreased by targeting the COX-1 but not COX-2 pathway." | 1.35 | VEGF expression and the effect of NSAIDs on ascites cell proliferation in the hen model of ovarian cancer. ( Giles, JR; Johnson, PA; Urick, ME, 2008) |
| "Four epithelial ovarian cancer cell lines (MDAH-2774, SKOV3, OVCAR and CaOV-3) were treated with the specific cyclooxygenase-2 inhibitor NS398 (10 or 100 mumol/l) and docetaxel (0." | 1.34 | The effects of combining docetaxel and cyclooxygenase-2 inhibitors on proliferation and apoptosis in epithelial ovarian cancer. ( Ali-Fehmi, R; Elhammady, E; Jiang, JZ; Malone, JM; Munkarah, AR; Saed, GM, 2007) |
| "Apoptosis was observed in primary ovarian cancer cell culture treated with COX-2 inhibitor." | 1.31 | Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. ( Barnes, MN; Grizzle, WE; Myers, RB; Oelschlager, DK; Partridge, EE; Rodríguez-Burford, C; Talley, LI, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (71.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Liang, Y | 1 |
| Wang, J | 1 |
| Wang, M | 2 |
| Lin, HY | 1 |
| Delmas, D | 1 |
| Vang, O | 1 |
| Hsieh, TC | 1 |
| Lin, S | 1 |
| Cheng, GY | 1 |
| Chiang, HL | 1 |
| Chen, CE | 1 |
| Tang, HY | 1 |
| Crawford, DR | 1 |
| Whang-Peng, J | 1 |
| Hwang, J | 1 |
| Liu, LF | 1 |
| Wu, JM | 1 |
| Qiu, X | 1 |
| Cheng, JC | 1 |
| Chang, HM | 1 |
| Leung, PC | 1 |
| Sonnemann, J | 1 |
| Hüls, I | 1 |
| Sigler, M | 1 |
| Palani, CD | 1 |
| Hong, le TT | 1 |
| Völker, U | 1 |
| Kroemer, HK | 1 |
| Beck, JF | 1 |
| Urick, ME | 1 |
| Giles, JR | 1 |
| Johnson, PA | 1 |
| Uddin, S | 1 |
| Ahmed, M | 1 |
| Hussain, A | 1 |
| Assad, L | 1 |
| Al-Dayel, F | 1 |
| Bavi, P | 1 |
| Al-Kuraya, KS | 1 |
| Munkarah, A | 1 |
| Munkarah, AR | 2 |
| Genhai, Z | 1 |
| Morris, R | 1 |
| Baker, VV | 1 |
| Deppe, G | 1 |
| Diamond, MP | 1 |
| Saed, GM | 2 |
| Wang, CY | 1 |
| Wang, XY | 1 |
| Zhang, SL | 1 |
| Wang, YX | 1 |
| Li, LK | 1 |
| Denkert, C | 1 |
| Fürstenberg, A | 1 |
| Daniel, PT | 1 |
| Koch, I | 1 |
| Köbel, M | 1 |
| Weichert, W | 1 |
| Siegert, A | 1 |
| Hauptmann, S | 1 |
| Spinella, F | 1 |
| Rosanò, L | 1 |
| Di Castro, V | 1 |
| Nicotra, MR | 1 |
| Natali, PG | 1 |
| Bagnato, A | 1 |
| Kang, S | 1 |
| Luo, R | 1 |
| Smicun, Y | 1 |
| Fishman, DA | 1 |
| Meng, Y | 1 |
| Barnes, AP | 1 |
| Miller, BE | 1 |
| Kucera, GL | 1 |
| Ali-Fehmi, R | 1 |
| Jiang, JZ | 1 |
| Elhammady, E | 1 |
| Malone, JM | 1 |
| Rodríguez-Burford, C | 1 |
| Barnes, MN | 1 |
| Oelschlager, DK | 1 |
| Myers, RB | 1 |
| Talley, LI | 1 |
| Partridge, EE | 1 |
| Grizzle, WE | 1 |
14 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Ovarian Neoplasms
| Article | Year |
|---|---|
Effect of NS-398, a cyclooxygenase-2 selective inhibitor, on the cytotoxicity of cytotoxic T lymphocytes to ovarian carcinoma cells.
Topics: Apoptosis; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystadenocarcinoma, Se | 2013 |
Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Ceramide | 2013 |
COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion.
Topics: Cadherins; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regul | 2014 |
Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.
Topics: Apoptosis; Aspirin; Cell Line, Tumor; Cyclooxygenase Inhibitors; Drug Synergism; Enzyme Inhibitors; | 2008 |
VEGF expression and the effect of NSAIDs on ascites cell proliferation in the hen model of ovarian cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Aspirin; Cell Growth Processes; Chickens; | 2008 |
Cyclooxygenase-2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer.
Topics: Animals; Apoptosis; Aspirin; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; C | 2010 |
Inhibition of paclitaxel-induced apoptosis by the specific COX-2 inhibitor, NS398, in epithelial ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspiri | 2003 |
[Inhibitory effect of NS398 on the proliferation of human ovarian cancer cell lines CAOV3 and OVCAR3 in vitro].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cyclooxygenase Inhibitors; Female | 2003 |
Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Line, Tumor; Cell Survival; Cyclooxygen | 2003 |
Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells.
Topics: Animals; Atrasentan; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cy | 2004 |
Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.
Topics: Animals; Antigen Presentation; Antigens, Surface; Apoptosis; Aspirin; Cell Line, Tumor; Cell Membran | 2006 |
Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cyclooxygenase | 2007 |
The effects of combining docetaxel and cyclooxygenase-2 inhibitors on proliferation and apoptosis in epithelial ovarian cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Cycle; Cel | 2007 |
Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biopsy; Blotting, Wester | 2002 |