n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Osteosarcoma in 8 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood." | 1.34 | Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells. ( Choe, M; Choi, EM; Ha, KS; Han, JA; Kim, H; Kim, JI; Kim, SR; Kim, SS; Kim, YM; Lee, EJ; Park, JH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbey, S | 1 |
| Goossens, L | 1 |
| Taverne, T | 1 |
| Cornet, J | 1 |
| Choesmel, V | 1 |
| Rouaud, C | 1 |
| Gimeno, G | 1 |
| Yannic-Arnoult, S | 1 |
| Michaux, C | 1 |
| Charlier, C | 1 |
| Houssin, R | 1 |
| Hénichart, JP | 1 |
| Matsuda, T | 1 |
| Kondo, A | 1 |
| Tsunashima, Y | 1 |
| Togari, A | 1 |
| Duan, DP | 1 |
| Dang, XQ | 1 |
| Wang, KZ | 1 |
| Wang, YP | 1 |
| Zhang, H | 1 |
| You, WL | 1 |
| Huang, FM | 1 |
| Chou, MY | 1 |
| Chang, YC | 1 |
| Coetzee, M | 1 |
| Haag, M | 1 |
| Claassen, N | 1 |
| Kruger, MC | 1 |
| Lee, EJ | 1 |
| Choi, EM | 1 |
| Kim, SR | 1 |
| Park, JH | 1 |
| Kim, H | 1 |
| Ha, KS | 1 |
| Kim, YM | 1 |
| Kim, SS | 1 |
| Choe, M | 1 |
| Kim, JI | 1 |
| Han, JA | 1 |
| Moalic, S | 1 |
| Liagre, B | 2 |
| Le Bail, JC | 1 |
| Beneytout, JL | 2 |
| Moalic-Juge, S | 1 |
| Duval, R | 1 |
| Corbiere, C | 1 |
| Bianchi, A | 1 |
| Bordji, K | 1 |
| Bosgiraud, C | 1 |
8 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Osteosarcoma
| Article | Year |
|---|---|
Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2002 |
Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Topics: Adult; Anticoagulants; Bone Neoplasms; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygena | 2010 |
The cyclooxygenase-2 inhibitor NS-398 inhibits proliferation and induces apoptosis in human osteosarcoma cells via downregulation of the survivin pathway.
Topics: Animals; Apoptosis; Bone Neoplasms; Caspase 3; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Down | 2012 |
Induction of cyclooxygenase-2 mRNA and protein expression by epoxy resin and zinc oxide-eugenol based root canal sealers in human osteoblastic cells.
Topics: Cells, Cultured; Cyclooxygenase 2; Epoxy Resins; Gene Expression Regulation, Enzymologic; Humans; Is | 2003 |
Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells.
Topics: Animals; Arachidonic Acid; Cell Line; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase Inhibitors; | 2005 |
Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells.
Topics: Bone Neoplasms; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Cy | 2007 |
Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor.
Topics: Adenovirus E1A Proteins; Apoptosis; Arachidonic Acid; bcl-2-Associated X Protein; Blotting, Western; | 2001 |
The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bone Neoplasms; Caspase 3; Caspases; Cyclin-Depe | 2002 |