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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Osteoarthritis

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Osteoarthritis in 6 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, L1
Feng, L1
Jia, Q1
Xu, J1
Wang, R1
Wang, Z1
Wu, Y1
Li, Y1
Paredes, Y1
Massicotte, F1
Pelletier, JP2
Martel-Pelletier, J2
Laufer, S1
Lajeunesse, D1
Jüngel, A1
Distler, O1
Schulze-Horsel, U1
Huber, LC1
Ha, HR1
Simmen, B1
Kalden, JR1
Pisetsky, DS1
Gay, S1
Distler, JH1
Grimmer, C1
Pfander, D1
Swoboda, B1
Aigner, T1
Mueller, L1
Hennig, FF1
Gelse, K1
Manabe, N1
Oda, H1
Nakamura, K1
Kuga, Y1
Uchida, S1
Kawaguchi, H1
Di Battista, JA1
Fahmi, H1
He, Y1
Zhang, M1

Other Studies

6 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Osteoarthritis

ArticleYear
Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: Animals; beta-Glucosidase; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2011
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:7

    Topics: Acetates; Alkaline Phosphatase; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Female;

2002
Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:11

    Topics: Arachidonic Acids; Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibito

2007
Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:12

    Topics: 2-Methoxyestradiol; Aged; Amino Acids, Dicarboxylic; Cartilage, Articular; Cell Hypoxia; Cells, Cult

2007
Involvement of fibroblast growth factor-2 in joint destruction of rheumatoid arthritis patients.
    Rheumatology (Oxford, England), 1999, Volume: 38, Issue:8

    Topics: Animals; Arthritis, Rheumatoid; Bone Resorption; Calcium; Cell Differentiation; Coculture Techniques

1999
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
    Clinical and experimental rheumatology, 2001, Volume: 19, Issue:1 Suppl 22

    Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenas

2001