n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Neoplasm Metastasis in 6 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bone is the most common site for breast cancer spread." | 1.48 | The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis. ( Bendinelli, P; Desiderio, MA; Maroni, P; Matteucci, E, 2018) |
| "Using a murine model of metastatic breast cancer, we show that PGE(2) levels are positively correlated with increased tumorigenic and metastatic potential." | 1.31 | Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer. ( Dorsey, R; Fulton, AM; Kundu, N; Yang, Q, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lemay, R | 1 |
| Lepage, M | 1 |
| Tremblay, L | 1 |
| Therriault, H | 1 |
| Charest, G | 1 |
| Paquette, B | 1 |
| Maroni, P | 1 |
| Bendinelli, P | 1 |
| Matteucci, E | 1 |
| Desiderio, MA | 1 |
| Lin, J | 1 |
| Wu, H | 1 |
| Shi, H | 1 |
| Pan, W | 1 |
| Yu, H | 1 |
| Zhu, J | 1 |
| Amano, H | 1 |
| Ito, Y | 1 |
| Suzuki, T | 1 |
| Kato, S | 1 |
| Matsui, Y | 1 |
| Ogawa, F | 1 |
| Murata, T | 1 |
| Sugimoto, Y | 1 |
| Senior, R | 1 |
| Kitasato, H | 1 |
| Hayashi, I | 1 |
| Satoh, Y | 1 |
| Narumiya, S | 1 |
| Majima, M | 1 |
| Liu, XH | 1 |
| Kirschenbaum, A | 1 |
| Yao, S | 1 |
| Stearns, ME | 1 |
| Holland, JF | 1 |
| Claffey, K | 1 |
| Levine, AC | 1 |
| Kundu, N | 1 |
| Yang, Q | 1 |
| Dorsey, R | 1 |
| Fulton, AM | 1 |
6 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Neoplasm Metastasis
| Article | Year |
|---|---|
Tumor Cell Invasion Induced by Radiation in Balb/C Mouse is Prevented by the Cox-2 Inhibitor NS-398.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2 Inhibitors; Drug Screening Assays, Antitu | 2017 |
The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Femal | 2018 |
Combined inhibition of epidermal growth factor receptor and cyclooxygenase-2 leads to greater anti-tumor activity of docetaxel in advanced prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Proliferation; Cyclooxygen | 2013 |
Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinase-9 and vascular endothelial growth factor during enhancement of tumor metastasis.
Topics: Animals; Cyclooxygenase 2; Humans; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neopl | 2009 |
Upregulation of vascular endothelial growth factor by cobalt chloride-simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line.
Topics: Androgens; Cell Hypoxia; Cobalt; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib | 1999 |
Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer.
Topics: Animals; Breast Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy | 2001 |