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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Necrosis

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Necrosis in 3 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" In this study, NS-398, a specific COX-2 inhibitor, and indomethacin, a COX-1 and COX-2 inhibitor, were administered 24 h after chloroform dosing to determine their effect on liver injury in Sprague-Dawley rats."5.32Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury. ( Begay, CK; Gandolfi, AJ, 2003)
" In this study, NS-398, a specific COX-2 inhibitor, and indomethacin, a COX-1 and COX-2 inhibitor, were administered 24 h after chloroform dosing to determine their effect on liver injury in Sprague-Dawley rats."1.32Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury. ( Begay, CK; Gandolfi, AJ, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Panaro, MA1
Pricci, M1
Meziani, F1
Ragot, T1
Andriantsitohaina, R1
Mitolo, V1
Tesse, A1
Begay, CK1
Gandolfi, AJ1
Saito, H1
Inagaki, Y1
Tsunenari, T1
Ura, M1
Mizuno, H1
Fujimoto-Ouchi, K1
Onuma, E1
Sato, K1
Ogata, E1
Yamada-Okabe, H1

Other Studies

3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Necrosis

ArticleYear
Cyclooxygenase-2-derived prostacyclin protective role on endotoxin-induced mouse cardiomyocyte mortality.
    Cardiovascular toxicology, 2011, Volume: 11, Issue:4

    Topics: Animals; Apoptosis; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Antagonism; D

2011
Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury.
    Toxicology, 2003, Mar-14, Volume: 185, Issue:1-2

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cyclooxygenase In

2003
Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma.
    Cancer science, 2007, Volume: 98, Issue:10

    Topics: Animals; Becaplermin; Biomarkers, Tumor; Cachexia; Calcium; Colonic Neoplasms; Cyclooxygenase 2; Cyc

2007