n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Muscle Contraction in 23 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test whether hemorrhagic shock (HS) increases the Cyclooxygenase-2 (COX-2) expression in the intestine and whether this enhanced COX-2 expression mediates the intestinal dysmotility after HS." | 1.42 | Enhanced cyclooxygenase-2 activity leads to intestinal dysmotility following hemorrhagic shock. ( Hao, XQ; Tian, YT; Zhang, LM; Zhang, YP, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 12 (52.17) | 29.6817 |
| 2010's | 7 (30.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CC | 2 |
| Lin, YM | 3 |
| Gao, J | 1 |
| Winston, JH | 1 |
| Cheng, LK | 1 |
| Shi, XZ | 3 |
| Ok, SH | 1 |
| Byon, HJ | 1 |
| Jin, H | 1 |
| Kim, HJ | 1 |
| Kim, W | 1 |
| Nam, IK | 1 |
| Eun, SY | 1 |
| Sohn, JT | 1 |
| Fu, Y | 1 |
| Xu, GY | 1 |
| Huang, LY | 1 |
| Zhang, YP | 1 |
| Hao, XQ | 1 |
| Zhang, LM | 1 |
| Tian, YT | 1 |
| Castillo-Hernandez, MC | 1 |
| Guevara-Balcazar, G | 1 |
| Lopez-Sanchez, P | 1 |
| Asbun-Bojalil, J | 1 |
| Lopez, RM | 1 |
| Castillo, EF | 1 |
| Castillo-Henkel, C | 1 |
| Lee, SY | 1 |
| Lee, MY | 1 |
| Park, SH | 1 |
| Kim, TH | 1 |
| Moon, YT | 1 |
| Han, JH | 1 |
| Myung, SC | 1 |
| Powell, DW | 1 |
| Sarna, SK | 1 |
| Briones, AM | 1 |
| Alonso, MJ | 1 |
| Hernanz, R | 1 |
| Tovar, S | 1 |
| Vila, E | 1 |
| Salaices, M | 1 |
| Huang, JC | 1 |
| Arbab, F | 1 |
| Tumbusch, KJ | 1 |
| Goldsby, JS | 1 |
| Matijevic-Aleksic, N | 1 |
| Wu, KK | 1 |
| El Sayah, M | 1 |
| Calixto, JB | 1 |
| Nakahara, T | 1 |
| Kubota, Y | 1 |
| Saito, M | 1 |
| Sakamoto, K | 1 |
| Ishii, K | 1 |
| Jerde, TJ | 2 |
| Calamon-Dixon, JL | 1 |
| Bjorling, DE | 2 |
| Nakada, SY | 2 |
| Guo, Z | 1 |
| Su, W | 1 |
| Allen, S | 1 |
| Pang, H | 1 |
| Daugherty, A | 1 |
| Smart, E | 1 |
| Gong, MC | 1 |
| Hashitani, H | 1 |
| Yanai, Y | 1 |
| Shirasawa, N | 1 |
| Soji, T | 1 |
| Tomita, A | 1 |
| Kohri, K | 1 |
| Suzuki, H | 1 |
| Mewe, M | 1 |
| Bauer, CK | 1 |
| Schwarz, JR | 1 |
| Middendorff, R | 1 |
| Ito, S | 1 |
| Kume, H | 1 |
| Oguma, T | 1 |
| Ito, Y | 1 |
| Kondo, M | 1 |
| Shimokata, K | 1 |
| Suki, B | 1 |
| Naruse, K | 1 |
| Beverelli, F | 1 |
| Béa, ML | 1 |
| Puybasset, L | 1 |
| Giudicelli, JF | 1 |
| Berdeaux, A | 1 |
| Zerrouk, A | 1 |
| Auguet, M | 1 |
| Chabrier, PE | 1 |
| Meini, S | 1 |
| Lecci, A | 1 |
| Cucchi, P | 1 |
| Catalioto, RM | 1 |
| Criscuoli, M | 1 |
| Maggi, CA | 1 |
| Saban, R | 1 |
| Davidson, ME | 1 |
| Lang, RJ | 1 |
| Miller, MR | 1 |
| Johnson, FC | 1 |
| Poyser, NL | 1 |
| Mastrangelo, D | 1 |
| Wisard, M | 1 |
| Rohner, S | 1 |
| Leisinger, H | 1 |
| Iselin, CE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing In Vitro Fertilization (IVF)[NCT02591186] | 60 participants (Actual) | Interventional | 2015-11-01 | Completed | |||
| Pilot Study to Examine Iloprost Can Enhance Human Assisted Reproductive Technology Pregnancy Outcomes.[NCT01549171] | 100 participants (Anticipated) | Observational | 2010-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Muscle Contraction
| Article | Year |
|---|---|
Are interstitial cells of Cajal involved in mechanical stress-induced gene expression and impairment of smooth muscle contractility in bowel obstruction?
Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Fluorescent Antibody Techni | 2013 |
Dexmedetomidine-induced contraction involves c-Jun NH2 -terminal kinase phosphorylation through activation of the 5-lipoxygenase pathway in the isolated endothelium-denuded rat aorta.
Topics: Animals; Aorta, Thoracic; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase 2 Inhibitors; D | 2014 |
Colon distention induces persistent visceral hypersensitivity by mechanotranscription of pain mediators in colonic smooth muscle cells.
Topics: Action Potentials; Animals; Cells, Cultured; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; G | 2015 |
Enhanced cyclooxygenase-2 activity leads to intestinal dysmotility following hemorrhagic shock.
Topics: Acetylcholine; Animals; Cyclooxygenase 2; Dinoprostone; Duodenum; Gastrointestinal Motility; Male; M | 2015 |
The influence of constitutive COX-2 in smooth muscle tissue on the contractile effect of phenylephrine in the rat abdominal aorta.
Topics: Animals; Aorta, Abdominal; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibit | 2010 |
NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2010 |
Pathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2.
Topics: Animals; Colon; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gastrointestinal Motili | 2011 |
Hypertension alters the participation of contractile prostanoids and superoxide anions in lipopolysaccharide effects on small mesenteric arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2; Dexamethasone; Dose-Response Rel | 2002 |
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochro | 2002 |
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochro | 2002 |
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochro | 2002 |
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochro | 2002 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Resp | 2003 |
Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats.
Topics: Animals; Cyclooxygenase 2; Cyclophosphamide; Cystitis; Dinoprostone; In Vitro Techniques; Indomethac | 2004 |
Celecoxib inhibits ureteral contractility and prostanoid release.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase Inhibitors; Depression, Chemical; D | 2005 |
COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice.
Topics: Animals; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Female; Gene Expression Profiling; Mice; Mice, | 2005 |
Interaction between spontaneous and neurally mediated regulation of smooth muscle tone in the rabbit corpus cavernosum.
Topics: Action Potentials; Animals; Calcium; Calcium Channels, L-Type; Chloride Channels; Cyclooxygenase 2 I | 2005 |
Mechanisms regulating spontaneous contractions in the bovine epididymal duct.
Topics: Animals; Calcium; Calcium Channels; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost | 2006 |
Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cations; Cyclooxygenas | 2006 |
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Coronary Vessels; Cyclooxygenase 1; Dogs; Enzyme | 1997 |
Augmented endothelium-dependent contraction to angiotensin II in the SHR aorta: role of an inducible cyclooxygenase metabolite.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cyclohex | 1998 |
Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists.
Topics: Animals; Bradykinin; Cystitis; Dinoprostone; In Vitro Techniques; Ketoprofen; Male; Muscle Contracti | 1998 |
Selective cyclooxygenase-2 inhibitors reduce ureteral contraction in vitro: a better alternative for renal colic?
Topics: Animals; Colic; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Indometh | 2000 |
Effects of selective inhibitors of cyclo-oxygenase-1 (COX-1) and cyclo-oxygenase-2 (COX-2) on the spontaneous myogenic contractions in the upper urinary tract of the guinea-pig and rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase | 2000 |
Endogenous prostaglandin formation in the field-stimulated guinea-pig vas deferens: comparison of the inhibitory effects of indomethacin and NS-398.
Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Guinea Pig | 1999 |
Diclofenac and NS-398, a selective cyclooxygenase-2 inhibitor, decrease agonist-induced contractions of the pig isolated ureter.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Free | 2000 |