n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Melanoma in 6 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sequential treatment of melanoma cells, first with gamma-irradiation to upregulate TRAIL-R surface expression, and then with resveratrol to suppress antiapoptotic proteins cFLIP and Bcl-xL and induce TRAIL surface expression, had dramatic effects on upregulation of apoptosis in some melanoma lines, including SW1 and WM35." | 1.35 | Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival. ( Hei, TK; Ivanov, VN; Johnson, GE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muraki, C | 1 |
| Ohga, N | 1 |
| Hida, Y | 1 |
| Nishihara, H | 1 |
| Kato, Y | 1 |
| Tsuchiya, K | 1 |
| Matsuda, K | 1 |
| Totsuka, Y | 1 |
| Shindoh, M | 1 |
| Hida, K | 1 |
| Duff, M | 1 |
| Stapleton, PP | 1 |
| Mestre, JR | 1 |
| Maddali, S | 1 |
| Smyth, GP | 1 |
| Yan, Z | 1 |
| Freeman, TA | 1 |
| Daly, JM | 1 |
| Denkins, Y | 1 |
| Kempf, D | 1 |
| Ferniz, M | 1 |
| Nileshwar, S | 1 |
| Marchetti, D | 1 |
| Ivanov, VN | 2 |
| Hei, TK | 2 |
| Johnson, GE | 1 |
| Denkert, C | 1 |
| Köbel, M | 1 |
| Berger, S | 1 |
| Siegert, A | 1 |
| Leclere, A | 1 |
| Trefzer, U | 1 |
| Hauptmann, S | 1 |
6 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Melanoma
| Article | Year |
|---|---|
Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells.
Topics: Animals; Blotting, Western; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cy | 2012 |
Cyclooxygenase-2 inhibition improves macrophage function in melanoma and increases the antineoplastic activity of interferon gamma.
Topics: Animals; Antineoplastic Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibi | 2003 |
Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Cyclooxygenase 2; D | 2005 |
Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells.
Topics: Apoptosis; Arsenites; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, | 2006 |
Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Chromones; Combined Modality Therapy; Cyclooxygena | 2008 |
Expression of cyclooxygenase 2 in human malignant melanoma.
Topics: Biocompatible Materials; Cell Division; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc | 2001 |