Page last updated: 2024-11-01

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Hormone-Dependent Neoplasms

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Hormone-Dependent Neoplasms in 3 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors."1.33Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition. ( Brueggemeier, RW; Diaz-Cruz, ES; Landini, S; Su, B, 2006)
"To investigate the function of COX-2 in prostate cancer directly, we stably transfected human full-length COX-2 cDNA into LNCaP cells (LNCaP-COX-2), which express low levels of endogenous COX-2."1.31Cyclooxygenase-2 promotes prostate cancer progression. ( Fujita, H; Keller, ET; Koshida, K; Mizokami, A; Namiki, M; Takahashi, Y; Yoshimito, T, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Su, B1
Diaz-Cruz, ES1
Landini, S1
Brueggemeier, RW1
Fujita, H1
Koshida, K1
Keller, ET1
Takahashi, Y1
Yoshimito, T1
Namiki, M1
Mizokami, A1
Liu, XH1
Kirschenbaum, A1
Yao, S1
Stearns, ME1
Holland, JF1
Claffey, K1
Levine, AC1

Other Studies

3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Hormone-Dependent Neoplasms

ArticleYear
Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition.
    Journal of medicinal chemistry, 2006, Feb-23, Volume: 49, Issue:4

    Topics: Aniline Compounds; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cyclooxygena

2006
Cyclooxygenase-2 promotes prostate cancer progression.
    The Prostate, 2002, Nov-01, Volume: 53, Issue:3

    Topics: Animals; Blotting, Western; Cell Division; Cyclooxygenase 2; Endothelial Growth Factors; Gene Expres

2002
Upregulation of vascular endothelial growth factor by cobalt chloride-simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line.
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:8

    Topics: Androgens; Cell Hypoxia; Cobalt; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib

1999