n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Hormone-Dependent Neoplasms in 3 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors." | 1.33 | Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition. ( Brueggemeier, RW; Diaz-Cruz, ES; Landini, S; Su, B, 2006) |
| "To investigate the function of COX-2 in prostate cancer directly, we stably transfected human full-length COX-2 cDNA into LNCaP cells (LNCaP-COX-2), which express low levels of endogenous COX-2." | 1.31 | Cyclooxygenase-2 promotes prostate cancer progression. ( Fujita, H; Keller, ET; Koshida, K; Mizokami, A; Namiki, M; Takahashi, Y; Yoshimito, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Su, B | 1 |
| Diaz-Cruz, ES | 1 |
| Landini, S | 1 |
| Brueggemeier, RW | 1 |
| Fujita, H | 1 |
| Koshida, K | 1 |
| Keller, ET | 1 |
| Takahashi, Y | 1 |
| Yoshimito, T | 1 |
| Namiki, M | 1 |
| Mizokami, A | 1 |
| Liu, XH | 1 |
| Kirschenbaum, A | 1 |
| Yao, S | 1 |
| Stearns, ME | 1 |
| Holland, JF | 1 |
| Claffey, K | 1 |
| Levine, AC | 1 |
3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition.
Topics: Aniline Compounds; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cyclooxygena | 2006 |
Cyclooxygenase-2 promotes prostate cancer progression.
Topics: Animals; Blotting, Western; Cell Division; Cyclooxygenase 2; Endothelial Growth Factors; Gene Expres | 2002 |
Upregulation of vascular endothelial growth factor by cobalt chloride-simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line.
Topics: Androgens; Cell Hypoxia; Cobalt; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib | 1999 |