n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Endotoxin Shock in 4 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a rat endotoxin shock model, expression of COX-2 plays a role in an increase in COX activity." | 1.30 | Selective inhibition of cyclooxygenase-2 by NS-398 in endotoxin shock rats in vivo. ( Futaki, N; Higuchi, S; Kitagawa, T; Takahashi, S; Tanaka, M; Yamakawa, Y, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elkamhawy, A | 1 |
| Kim, NY | 1 |
| Hassan, AHE | 1 |
| Park, JE | 1 |
| Paik, S | 1 |
| Yang, JE | 1 |
| Oh, KS | 1 |
| Lee, BH | 1 |
| Lee, MY | 1 |
| Shin, KJ | 1 |
| Pae, AN | 1 |
| Lee, KT | 1 |
| Roh, EJ | 1 |
| Qian, X | 1 |
| Zhang, J | 1 |
| Liu, J | 1 |
| Tunctan, B | 1 |
| Korkmaz, B | 1 |
| Cuez, T | 1 |
| Kemal Buharalioglu, C | 1 |
| Sahan-Firat, S | 1 |
| Falck, J | 1 |
| Malik, KU | 1 |
| Futaki, N | 1 |
| Takahashi, S | 1 |
| Kitagawa, T | 1 |
| Yamakawa, Y | 1 |
| Tanaka, M | 1 |
| Higuchi, S | 1 |
4 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Endotoxin Shock
| Article | Year |
|---|---|
Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents.
Topics: Allosteric Regulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultu | 2020 |
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; C | 2011 |
Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats.
Topics: Animals; Blood Pressure; Cyclooxygenase 2 Inhibitors; Eicosanoids; Hypotension; Lipopolysaccharides; | 2010 |
Selective inhibition of cyclooxygenase-2 by NS-398 in endotoxin shock rats in vivo.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Lipop | 1997 |