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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Colitis

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Colitis in 5 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Acute colitis is characterized by an extensive disturbance of microcirculation together with signs of systemic inflammatory response syndrome."1.33Selective COX-2 inhibition reduces leukocyte sticking and improves the microcirculation in TNBS colitis. ( Anderson, T; Buhr, HJ; Kruschewski, M; Loddenkemper, C, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massoumi, R1
Nielsen, CK1
Azemovic, D1
Sjölander, A1
Kruschewski, M1
Anderson, T1
Buhr, HJ1
Loddenkemper, C1
Piston, D1
Wang, S1
Feng, Y1
Ye, YJ1
Zhou, J1
Jiang, KW1
Xu, F1
Zhao, Y1
Cui, ZR1
Lesch, CA1
Kraus, ER1
Sanchez, B1
Gilbertsen, R1
Guglietta, A1
Morteau, O1
Morham, SG1
Sellon, R1
Dieleman, LA1
Langenbach, R1
Smithies, O1
Sartor, RB1

Other Studies

5 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Colitis

ArticleYear
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin.
    Experimental cell research, 2003, Oct-01, Volume: 289, Issue:2

    Topics: Caco-2 Cells; Carcinoma; Cell Adhesion; Colitis; Collagen Type I; Colonic Neoplasms; Cyclooxygenase

2003
Selective COX-2 inhibition reduces leukocyte sticking and improves the microcirculation in TNBS colitis.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:4

    Topics: Animals; Colitis; Colon; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Immunohistochemistry;

2006
The role of cyclooxygenase-2/prostanoid pathway in visceral pain induced liver stress response in rats.
    Chinese medical journal, 2007, Oct-20, Volume: 120, Issue:20

    Topics: Acute Disease; Animals; Colitis; Cyclooxygenase 2; Hyperalgesia; Liver; Liver Diseases; Male; Morphi

2007
Lack of beneficial effect of COX-2 inhibitors in an experimental model of colitis.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi

1999
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo

2000