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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Chronic Illness

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Chronic Illness in 5 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Epileptic seizures drive expression of the blood-brain barrier efflux transporter P-glycoprotein via a glutamate/cyclooxygenase-2 mediated signalling pathway."1.36COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. ( Aronica, E; Edelbroek, PM; Gorter, JA; Holtman, L; Pekcec, A; Potschka, H; Schlichtiger, J; van Vliet, EA; Zibell, G, 2010)
"In vehicle-treated rats, gastric ulcers healed progressively and at day 14 the healing was completed, accompanied by a significant rise in the GBF at ulcer margin."1.31Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers. ( Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Ptak, A; Sliwowski, Z, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Vliet, EA1
Zibell, G1
Pekcec, A1
Schlichtiger, J1
Edelbroek, PM1
Holtman, L1
Aronica, E1
Gorter, JA1
Potschka, H1
Poplawski, C1
Sosnowski, D1
Szaflarska-Popławska, A1
Sarosiek, J1
McCallum, R1
Bartuzi, Z1
Cong, P1
Pricolo, V1
Biancani, P1
Behar, J1
Brzozowski, T1
Konturek, PC1
Konturek, SJ1
Sliwowski, Z1
Pajdo, R1
Drozdowicz, D1
Ptak, A1
Hahn, EG1
Kim, TI1
Lee, YC1
Lee, KH1
Han, JH1
Chon, CY1
Moon, YM1
Kang, JK1
Park, IS1

Other Studies

5 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Chronic Illness

ArticleYear
COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri

2010
Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model.
    World journal of gastroenterology, 2006, Mar-21, Volume: 12, Issue:11

    Topics: Animals; Bile Acids and Salts; Chronic Disease; Cyclooxygenase Inhibitors; Dinoprostone; Disease Mod

2006
Abnormalities of prostaglandins and cyclooxygenase enzymes in female patients with slow-transit constipation.
    Gastroenterology, 2007, Volume: 133, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chronic Disease; Colon; Constipation; Cyclooxy

2007
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
    Microscopy research and technique, 2001, Jun-01, Volume: 53, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cycloo

2001
Effects of nonsteroidal anti-inflammatory drugs on Helicobacter pylori-infected gastric mucosae of mice: apoptosis, cell proliferation, and inflammatory activity.
    Infection and immunity, 2001, Volume: 69, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Chronic Disease; Cycloox

2001