n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Chemical and Drug Induced Liver Injury in 3 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, NS-398, a specific COX-2 inhibitor, and indomethacin, a COX-1 and COX-2 inhibitor, were administered 24 h after chloroform dosing to determine their effect on liver injury in Sprague-Dawley rats." | 5.32 | Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury. ( Begay, CK; Gandolfi, AJ, 2003) |
| " In this study, NS-398, a specific COX-2 inhibitor, and indomethacin, a COX-1 and COX-2 inhibitor, were administered 24 h after chloroform dosing to determine their effect on liver injury in Sprague-Dawley rats." | 1.32 | Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury. ( Begay, CK; Gandolfi, AJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, G | 1 |
| Han, C | 1 |
| Xu, L | 1 |
| Lim, K | 1 |
| Isse, K | 1 |
| Wu, T | 1 |
| Yoshioka, W | 1 |
| Higashiyama, W | 1 |
| Tohyama, C | 1 |
| Begay, CK | 1 |
| Gandolfi, AJ | 1 |
3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; ErbB Receptors; fas Re | 2009 |
Involvement of microRNAs in dioxin-induced liver damage in the mouse.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Down-Regulation; Liver; Male; Mic | 2011 |
Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cyclooxygenase In | 2003 |