n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cell Transformation, Neoplastic in 7 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "NS398, a selective cyclooxygenase-2 inhibitor, and simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, both exert an anticancer effect on hepatocellular carcinoma cells, but the effect of co-administration of the two drugs remains unknown." | 7.80 | Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line. ( Byun, KS; Hwang, JW; Hyun, JJ; Jung, SW; Kim, JH; Koo, JS; Lee, SJ; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Woo, SU; Yeon, JE; Yim, H; Yim, HJ, 2014) |
| "NS398, a selective cyclooxygenase-2 inhibitor, and simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, both exert an anticancer effect on hepatocellular carcinoma cells, but the effect of co-administration of the two drugs remains unknown." | 3.80 | Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line. ( Byun, KS; Hwang, JW; Hyun, JJ; Jung, SW; Kim, JH; Koo, JS; Lee, SJ; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Woo, SU; Yeon, JE; Yim, H; Yim, HJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SJ | 1 |
| Hwang, JW | 1 |
| Yim, H | 1 |
| Yim, HJ | 1 |
| Woo, SU | 1 |
| Suh, SJ | 1 |
| Hyun, JJ | 1 |
| Jung, SW | 1 |
| Koo, JS | 1 |
| Kim, JH | 1 |
| Seo, YS | 1 |
| Yeon, JE | 1 |
| Lee, SW | 1 |
| Byun, KS | 1 |
| Um, SH | 1 |
| Ferrario, A | 1 |
| Gomer, CJ | 1 |
| Liu, G | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
| Zhang, Y | 1 |
| Dong, Z | 1 |
| Wölfle, D | 1 |
| Bisht, KS | 1 |
| Bradbury, CM | 1 |
| Zoberi, I | 1 |
| Curry, HA | 1 |
| Kaushal, A | 1 |
| Roti Roti, JL | 1 |
| Gius, D | 1 |
| Zhang, X | 1 |
| Morham, SG | 1 |
| Langenbach, R | 1 |
| Young, DA | 1 |
| Nakanishi, Y | 1 |
| Kamijo, R | 1 |
| Takizawa, K | 1 |
| Hatori, M | 1 |
| Nagumo, M | 1 |
7 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor; | 2014 |
Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor.
Topics: Animals; Celecoxib; Cell Line, Tumor; Cell Transformation, Neoplastic; Combined Modality Therapy; Cy | 2010 |
NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2.
Topics: Animals; Blotting, Western; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase | 2003 |
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinopro | 2003 |
Inhibition of cyclooxygenase-2 with NS-398 and the prevention of radiation-induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells.
Topics: Animals; Cell Division; Cell Separation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxy | 2003 |
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line | 1999 |
Inhibitors of cyclooxygenase-2 (COX-2) suppressed the proliferation and differentiation of human leukaemia cell lines.
Topics: Antineoplastic Agents; Blotting, Western; Butanones; Cell Division; Cell Transformation, Neoplastic; | 2001 |