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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cell Transformation, Neoplastic

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cell Transformation, Neoplastic in 7 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"NS398, a selective cyclooxygenase-2 inhibitor, and simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, both exert an anticancer effect on hepatocellular carcinoma cells, but the effect of co-administration of the two drugs remains unknown."7.80Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line. ( Byun, KS; Hwang, JW; Hyun, JJ; Jung, SW; Kim, JH; Koo, JS; Lee, SJ; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Woo, SU; Yeon, JE; Yim, H; Yim, HJ, 2014)
"NS398, a selective cyclooxygenase-2 inhibitor, and simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, both exert an anticancer effect on hepatocellular carcinoma cells, but the effect of co-administration of the two drugs remains unknown."3.80Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line. ( Byun, KS; Hwang, JW; Hyun, JJ; Jung, SW; Kim, JH; Koo, JS; Lee, SJ; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Woo, SU; Yeon, JE; Yim, H; Yim, HJ, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, SJ1
Hwang, JW1
Yim, H1
Yim, HJ1
Woo, SU1
Suh, SJ1
Hyun, JJ1
Jung, SW1
Koo, JS1
Kim, JH1
Seo, YS1
Yeon, JE1
Lee, SW1
Byun, KS1
Um, SH1
Ferrario, A1
Gomer, CJ1
Liu, G1
Ma, WY1
Bode, AM1
Zhang, Y1
Dong, Z1
Wölfle, D1
Bisht, KS1
Bradbury, CM1
Zoberi, I1
Curry, HA1
Kaushal, A1
Roti Roti, JL1
Gius, D1
Zhang, X1
Morham, SG1
Langenbach, R1
Young, DA1
Nakanishi, Y1
Kamijo, R1
Takizawa, K1
Hatori, M1
Nagumo, M1

Other Studies

7 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cell Transformation, Neoplastic

ArticleYear
Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor;

2014
Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 635

    Topics: Animals; Celecoxib; Cell Line, Tumor; Cell Transformation, Neoplastic; Combined Modality Therapy; Cy

2010
NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Animals; Blotting, Western; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cyclooxygenase

2003
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
    Toxicology, 2003, Jun-30, Volume: 188, Issue:2-3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinopro

2003
Inhibition of cyclooxygenase-2 with NS-398 and the prevention of radiation-induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells.
    International journal of radiation biology, 2003, Volume: 79, Issue:11

    Topics: Animals; Cell Division; Cell Separation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxy

2003
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.
    The Journal of experimental medicine, 1999, Aug-16, Volume: 190, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line

1999
Inhibitors of cyclooxygenase-2 (COX-2) suppressed the proliferation and differentiation of human leukaemia cell lines.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:12

    Topics: Antineoplastic Agents; Blotting, Western; Butanones; Cell Division; Cell Transformation, Neoplastic;

2001