n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Carcinoma, Non-Small Cell Lung in 9 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lung cancer is frequently complicated by pulmonary infections which may impair prognosis of this disease." | 1.39 | Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation. ( Banat, GA; Dahlem, G; Eul, B; Fink, L; Goldmann, T; Grandel, U; Grimminger, F; Hattar, K; Lang, DS; Savai, R; Schermuly, RT; Schmall, A; Seeger, W; Sibelius, U; Subtil, FS; Vollmer, E; Wilhelm, J, 2013) |
| "NS-398 suppressed the growth of colon cancer cells, independent of COX-2 expression." | 1.33 | Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. ( Choi, CW; Kim, BS; Kim, JS; Kim, SJ; Kim, YH; Lee, YJ; Seo, JH; Shin, SW; Yoon, JH, 2005) |
| "As indomethacin was more effective we used it in mechanistic studies." | 1.32 | Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways. ( Bradbury, DA; Knox, AJ; Pang, L; Sánchez-Alcázar, JA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, GB | 1 |
| Fang, HY | 1 |
| Tao, DY | 1 |
| Chen, XP | 1 |
| Cao, FL | 1 |
| Ramer, R | 1 |
| Walther, U | 1 |
| Borchert, P | 1 |
| Laufer, S | 1 |
| Linnebacher, M | 1 |
| Hinz, B | 1 |
| Hattar, K | 2 |
| Franz, K | 1 |
| Ludwig, M | 1 |
| Sibelius, U | 2 |
| Wilhelm, J | 2 |
| Lohmeyer, J | 1 |
| Savai, R | 2 |
| Subtil, FS | 2 |
| Dahlem, G | 2 |
| Eul, B | 2 |
| Seeger, W | 2 |
| Grimminger, F | 2 |
| Grandel, U | 2 |
| Qiu, R | 1 |
| Chen, J | 1 |
| Sima, J | 1 |
| Shen, X | 1 |
| Liu, D | 1 |
| Shen, J | 1 |
| Schmall, A | 1 |
| Lang, DS | 1 |
| Goldmann, T | 1 |
| Fink, L | 1 |
| Schermuly, RT | 1 |
| Banat, GA | 1 |
| Vollmer, E | 1 |
| Sánchez-Alcázar, JA | 1 |
| Bradbury, DA | 1 |
| Pang, L | 1 |
| Knox, AJ | 1 |
| Han, S | 2 |
| Roman, J | 2 |
| Kim, SJ | 1 |
| Seo, JH | 1 |
| Lee, YJ | 1 |
| Yoon, JH | 1 |
| Choi, CW | 1 |
| Kim, BS | 1 |
| Shin, SW | 1 |
| Kim, YH | 1 |
| Kim, JS | 1 |
9 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
COX-2 potentiates cisplatin resistance of non-small cell lung cancer cells by promoting EMT in an AKT signaling pathway-dependent manner.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cispl | 2019 |
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib.
Topics: Anilides; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cell Line, Tu | 2013 |
Interactions between neutrophils and non-small cell lung cancer cells: enhancement of tumor proliferation and inflammatory mediator synthesis.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Communication; Cell Growth Processes; Cell Line, Tumor; Cocultu | 2014 |
NS398 induces apoptosis in non-small cell lung cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Growth Processes; Cell Line, Tumor; Cyclo | 2012 |
Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyc | 2013 |
Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.
Topics: Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspases; C | 2003 |
COX-2 inhibitors suppress integrin alpha5 expression in human lung carcinoma cells through activation of Erk: involvement of Sp1 and AP-1 sites.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cyclooxygenase Inhibitors; Extracellular Signal-Regul | 2005 |
Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Caco-2 Cells; Carcinoma, Non-Small-Cell Lung; Cell Line, T | 2005 |
COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals.
Topics: Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase Inhibitors; Flavonoids; | 2006 |