n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Carcinoma, Lewis Lung in 2 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report that indomethacin, a nonspecific inhibitor of COX, and NS398, a specific inhibitor of COX2, preserved muscle mass and reduced type 1 TNF receptors in muscles of mice bearing the Lewis lung carcinoma, but not in mice bearing the B16 melanoma." | 3.73 | Inhibitors of COX activity preserve muscle mass in mice bearing the Lewis lung carcinoma, but not the B16 melanoma. ( Graves, E; McCarthy, DO; Ramsay, E, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, S | 1 |
| Amano, H | 1 |
| Hayashi, I | 1 |
| Kitasato, H | 1 |
| Kamata, M | 1 |
| Inukai, M | 1 |
| Yoshimura, H | 1 |
| Majima, M | 1 |
| Graves, E | 1 |
| Ramsay, E | 1 |
| McCarthy, DO | 1 |
2 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo.
Topics: Animals; Antibodies, Blocking; Aspirin; Benzenesulfonates; Carcinoma, Lewis Lung; Cyclooxygenase Inh | 2003 |
Inhibitors of COX activity preserve muscle mass in mice bearing the Lewis lung carcinoma, but not the B16 melanoma.
Topics: Analysis of Variance; Animals; Cachexia; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Female; I | 2006 |