n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Carcinoma, Epidermoid in 22 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arecoline was found to elevate HSP27 expression in a dose- and time-dependent manner (P < 0." | 1.38 | Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas. ( Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yu, CC, 2012) |
| "Oral squamous cell carcinoma (OSCC) is the sixth most common cancer and frequently metastasizes to the cervical lymph nodes, leading to poor survival of patients with OSCC." | 1.38 | Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma. ( Hata, K; Morita, Y; Nakanishi, M; Nishisho, T; Yoneda, T; Yura, Y, 2012) |
| "The esophageal squamous cell carcinoma cell line TE-13 was cultured with NS-398 at different concentrations or for different times." | 1.35 | NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2. ( Drew, PA; Jamieson, GG; Liu, JF; Shan, BE; Wu, TC; Zhu, GJ; Zhu, TN, 2009) |
| "Worldwide oral squamous cell carcinoma (OSCC) represents about 5." | 1.33 | Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. ( Hart, IR; Marshall, JF; McCulloch, D; Nystrom, ML; Speight, PM; Thomas, GJ; Violette, SM; Weinreb, PH, 2006) |
| "In the present study, human oral squamous cell carcinoma (OSCC) cell lines NA and HSC-4 were used to evaluate the effects of NS-398, a selective inhibitor of COX-2, and COX-2 antisense oligonucleotide (COX-2 AS) on the invasion activity of OSCC cells." | 1.32 | Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44. ( Hatori, M; Ito, D; Ito, H; Kinugasa, Y; Kurihara, Y; Nagumo, M, 2004) |
| "NSAIDs similarly induce apoptosis in esophageal cancer cells, although the mechanisms of these effects remain to be defined." | 1.31 | Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. ( Chen, D; Fischer, SM; Lippman, SM; Lotan, R; Morris, JS; Shureiqi, I; Xu, X, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (77.27) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MF | 1 |
| Chen, PT | 1 |
| Lu, MS | 1 |
| Chen, WC | 1 |
| Fujii, R | 1 |
| Imanishi, Y | 1 |
| Shibata, K | 1 |
| Sakai, N | 1 |
| Sakamoto, K | 1 |
| Shigetomi, S | 1 |
| Habu, N | 1 |
| Otsuka, K | 1 |
| Sato, Y | 1 |
| Watanabe, Y | 1 |
| Ozawa, H | 1 |
| Tomita, T | 1 |
| Kameyama, K | 1 |
| Fujii, M | 1 |
| Ogawa, K | 1 |
| Du, Y | 1 |
| Zhang, S | 1 |
| Wang, Z | 1 |
| Zhou, W | 1 |
| Luan, M | 1 |
| Yang, X | 1 |
| Chen, N | 1 |
| Liu, JF | 1 |
| Zhu, GJ | 1 |
| Jamieson, GG | 1 |
| Wu, TC | 1 |
| Zhu, TN | 1 |
| Shan, BE | 1 |
| Drew, PA | 1 |
| Lee, SS | 1 |
| Tsai, CH | 1 |
| Ho, YC | 1 |
| Yu, CC | 1 |
| Chang, YC | 1 |
| Morita, Y | 1 |
| Hata, K | 1 |
| Nakanishi, M | 1 |
| Nishisho, T | 1 |
| Yura, Y | 1 |
| Yoneda, T | 1 |
| Sun, XJ | 2 |
| Xie, H | 1 |
| Wang, XK | 2 |
| Zhang, H | 1 |
| Song, CX | 1 |
| Zhang, YJ | 1 |
| Zeng, Q | 1 |
| McCauley, LK | 1 |
| Wang, CY | 1 |
| Kanda, N | 1 |
| Watanabe, S | 1 |
| Minter, HA | 1 |
| Eveson, JW | 1 |
| Huntley, S | 1 |
| Elder, DJ | 1 |
| Hague, A | 1 |
| Amirghahari, N | 1 |
| Harrison, L | 1 |
| Smith, M | 1 |
| Rong, X | 1 |
| Naumann, I | 1 |
| Ampil, F | 1 |
| Shi, R | 1 |
| Glass, J | 1 |
| Nathan, CO | 1 |
| Yu, HP | 1 |
| Shi, LY | 1 |
| Lu, WH | 1 |
| Su, YH | 1 |
| Li, YY | 1 |
| Xu, SQ | 1 |
| Kase, S | 1 |
| Osaki, M | 1 |
| Honjo, S | 1 |
| Takeda, A | 1 |
| Adachi, K | 1 |
| Araki, K | 1 |
| Ito, H | 2 |
| Kinugasa, Y | 1 |
| Hatori, M | 2 |
| Kurihara, Y | 1 |
| Ito, D | 2 |
| Nagumo, M | 3 |
| Zhi, H | 1 |
| Wang, L | 1 |
| Zhang, J | 1 |
| Zhou, C | 1 |
| Ding, F | 1 |
| Luo, A | 1 |
| Wu, M | 1 |
| Zhan, Q | 1 |
| Liu, Z | 1 |
| Kudryavtsev, IA | 1 |
| Gudkova, MV | 1 |
| Pavlova, OM | 1 |
| Oreshkin, AE | 1 |
| Myasishcheva, NV | 1 |
| Jia, LL | 1 |
| Wang, D | 1 |
| Chen, S | 1 |
| Feng, Y | 1 |
| Yang, Q | 1 |
| Campbell, BH | 1 |
| Tang, X | 1 |
| Campbell, WB | 1 |
| Nystrom, ML | 1 |
| McCulloch, D | 1 |
| Weinreb, PH | 1 |
| Violette, SM | 1 |
| Speight, PM | 1 |
| Marshall, JF | 1 |
| Hart, IR | 1 |
| Thomas, GJ | 1 |
| Sumitani, K | 2 |
| Kamijo, R | 2 |
| Toyoshima, T | 2 |
| Nakanishi, Y | 1 |
| Takizawa, K | 2 |
| Shureiqi, I | 1 |
| Xu, X | 1 |
| Chen, D | 1 |
| Lotan, R | 1 |
| Morris, JS | 1 |
| Fischer, SM | 1 |
| Lippman, SM | 1 |
22 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase 1 Family; Animals; Carcinoma, Squamous Cell; | 2018 |
Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma.
Topics: Antigens, CD; Antineoplastic Agents; Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxy | 2014 |
Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Proliferation; Cyclooxygenas | 2008 |
NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cel | 2009 |
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Catechin; Cyclooxy | 2012 |
Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 2012 |
[The influence of COX-2 depressant in angiogenesis of oral squamous cell carcinoma].
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Down-Regulation; Humans; Mo | 2012 |
Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression.
Topics: Animals; Anoikis; Apoptosis; Blotting, Northern; Blotting, Western; Carcinoma, Squamous Cell; Cell D | 2002 |
Cyclooxygenase-2 inhibitor enhances whereas prostaglandin E2 inhibits the production of interferon-induced protein of 10 kDa in epidermoid carcinoma A431.
Topics: Carcinoma, Squamous Cell; Chemokine CXCL10; Chemokines, CXC; Cyclic AMP; Cyclic AMP-Dependent Protei | 2002 |
The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycl | 2003 |
NS 398 radiosensitizes an HNSCC cell line by possibly inhibiting radiation-induced expression of COX-2.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibi | 2003 |
Expression of cyclooxygenase-2 (COX-2) in human esophageal cancer and in vitro inhibition by a specific COX-2 inhibitor, NS-398.
Topics: Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Division; Cyclooxygenase 2; Cyclooxyg | 2004 |
A selective cyclooxygenase-2 inhibitor, NS398, inhibits cell growth and induces cell cycle arrest in the G2/M phase in human esophageal squamous cell carcinoma cells.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Cyclin B; C | 2004 |
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
Topics: Carcinoma, Squamous Cell; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloox | 2004 |
Significance of COX-2 expression in human esophageal squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Disease Progres | 2006 |
Lipoxygenase pathway of arachidonic acid metabolism in growth control of tumor cells of different type.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenocarcinoma; Arachidonate Lipoxygenases; Arachidonic | 2005 |
[The inhibitive effect of COX-2 inhibitor NS-398 on cancer cell growth of human tongue squamous cell carcinoma].
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Humans; | 2006 |
Reduced expression of 15-lipoxygenase 2 in human head and neck carcinomas.
Topics: Arachidonate 15-Lipoxygenase; Carcinoma; Carcinoma, Squamous Cell; Cell Proliferation; Cells, Cultur | 2006 |
Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell | 2006 |
Specific inhibition of cyclooxygenase-2 results in inhibition of proliferation of oral cancer cell lines via suppression of prostaglandin E2 production.
Topics: Carcinoma, Squamous Cell; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygena | 2001 |
Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arachidonate 15-Lipoxygenase; Ca | 2001 |
Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Membrane; Cyclin-Dependent | 2002 |