n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cancer of Pancreas in 12 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These data indicated that P38 in the pancreatic cancer cells was non‑specifically activated by NS‑398." | 1.43 | NS-398 promotes pancreatic cancer cell invasion by CD147 and MMP-2 via the activation of P38. ( Gao, FH; Liu, H; Tang, MC; Xu, XF; Zhao, Y; Zhou, YQ, 2016) |
| "Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide." | 1.37 | Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells. ( Efferth, T; Hoheisel, JD; Youns, M, 2011) |
| "To investigate the role of COX-2 in pancreatic cancer, we evaluated COX-2 protein expression in primary human pancreatic adenocarcinomas (n = 23) and matched normal adjacent tissue (n = 11) by immunoblot analysis." | 1.31 | Cyclooxygenase-2 expression in human pancreatic adenocarcinomas. ( Barnard, DS; Billings, SD; Cheng, L; Crowell, PL; Heilman, DK; Lin, A; Marshall, MS; Marshall, SJ; Sweeney, CJ; Yip-Schneider, MT, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Xu, XF | 2 |
| Zhao, Y | 1 |
| Tang, MC | 1 |
| Zhou, YQ | 1 |
| Gao, FH | 1 |
| Kohi, S | 1 |
| Sato, N | 1 |
| Koga, A | 1 |
| Matayoshi, N | 1 |
| Hirata, K | 1 |
| Xie, CG | 1 |
| Wang, XP | 1 |
| Liu, J | 1 |
| Yu, YC | 1 |
| Hu, HL | 1 |
| Guo, CY | 1 |
| Sun, WH | 1 |
| Chen, GS | 1 |
| Ou, XL | 1 |
| Yang, Y | 1 |
| Luo, C | 1 |
| Zhang, Y | 1 |
| Shao, Y | 1 |
| Xu, HC | 1 |
| Xiao, B | 1 |
| Xue, YP | 1 |
| Zhou, SM | 1 |
| Zhao, QS | 1 |
| Ding, GX | 1 |
| Youns, M | 1 |
| Efferth, T | 1 |
| Hoheisel, JD | 1 |
| Levitt, RJ | 1 |
| Pollak, M | 1 |
| Chu, J | 1 |
| Lloyd, FL | 1 |
| Trifan, OC | 1 |
| Knapp, B | 1 |
| Rizzo, MT | 1 |
| Schmidt, CM | 1 |
| Wang, Y | 1 |
| Wiesenauer, C | 1 |
| Yoshida, S | 1 |
| Ujiki, M | 1 |
| Ding, XZ | 1 |
| Pelham, C | 1 |
| Talamonti, MS | 1 |
| Bell, RH | 1 |
| Denham, W | 1 |
| Adrian, TE | 1 |
| Huang, DS | 1 |
| Xu, X | 1 |
| Zheng, SS | 1 |
| Cheng, JF | 1 |
| Molina, MA | 1 |
| Sitja-Arnau, M | 1 |
| Lemoine, MG | 1 |
| Frazier, ML | 1 |
| Sinicrope, FA | 1 |
| Yip-Schneider, MT | 1 |
| Barnard, DS | 1 |
| Billings, SD | 1 |
| Cheng, L | 1 |
| Heilman, DK | 1 |
| Lin, A | 1 |
| Marshall, SJ | 1 |
| Crowell, PL | 1 |
| Marshall, MS | 1 |
| Sweeney, CJ | 1 |
12 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Pancreas
| Article | Year |
|---|---|
NS-398 promotes pancreatic cancer cell invasion by CD147 and MMP-2 via the activation of P38.
Topics: Basigin; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Humans; Imidazoles; MAP Kinase Sig | 2016 |
KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.
Topics: Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation | 2017 |
Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo.
Topics: Administration, Oral; Aged; Animals; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase | 2008 |
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells.
Topics: Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inh | 2009 |
Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Profiling; Humans; | 2011 |
Insulin-like growth factor-I antagonizes the antiproliferative effects of cyclooxygenase-2 inhibitors on BxPC-3 pancreatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Cycle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2002 |
Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer.
Topics: Capillaries; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloox | 2003 |
Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis.
Topics: Adenocarcinoma; Apoptosis; Butadienes; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Li | 2003 |
Pancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs.
Topics: Animals; Butadienes; Cell Proliferation; Cells, Cultured; Coculture Techniques; Culture Media, Condi | 2005 |
[NS398 induced apoptosis in pancreatic carcinoma cell strain BxPC-3 through a COX-2-in dependent pathway].
Topics: Apoptosis; Caspase 3; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Nitrobe | 2005 |
Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cyclooxygenase 1; Cyclooxyge | 1999 |
Cyclooxygenase-2 expression in human pancreatic adenocarcinomas.
Topics: Adenocarcinoma; Animals; Cell Line, Transformed; Codon; Cricetinae; Cyclooxygenase 2; Cyclooxygenase | 2000 |