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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Mouth

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cancer of Mouth in 9 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Arecoline was found to elevate HSP27 expression in a dose- and time-dependent manner (P < 0."1.38Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas. ( Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yu, CC, 2012)
"Oral squamous cell carcinoma (OSCC) is the sixth most common cancer and frequently metastasizes to the cervical lymph nodes, leading to poor survival of patients with OSCC."1.38Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma. ( Hata, K; Morita, Y; Nakanishi, M; Nishisho, T; Yoneda, T; Yura, Y, 2012)
"Worldwide oral squamous cell carcinoma (OSCC) represents about 5."1.33Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. ( Hart, IR; Marshall, JF; McCulloch, D; Nystrom, ML; Speight, PM; Thomas, GJ; Violette, SM; Weinreb, PH, 2006)
"In the present study, human oral squamous cell carcinoma (OSCC) cell lines NA and HSC-4 were used to evaluate the effects of NS-398, a selective inhibitor of COX-2, and COX-2 antisense oligonucleotide (COX-2 AS) on the invasion activity of OSCC cells."1.32Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44. ( Hatori, M; Ito, D; Ito, H; Kinugasa, Y; Kurihara, Y; Nagumo, M, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujii, R1
Imanishi, Y1
Shibata, K1
Sakai, N1
Sakamoto, K1
Shigetomi, S1
Habu, N1
Otsuka, K1
Sato, Y1
Watanabe, Y1
Ozawa, H1
Tomita, T1
Kameyama, K1
Fujii, M1
Ogawa, K1
Du, Y1
Zhang, S1
Wang, Z1
Zhou, W1
Luan, M1
Yang, X1
Chen, N1
Muraki, C1
Ohga, N1
Hida, Y1
Nishihara, H1
Kato, Y1
Tsuchiya, K1
Matsuda, K1
Totsuka, Y1
Shindoh, M1
Hida, K1
Lee, SS1
Tsai, CH1
Ho, YC1
Yu, CC1
Chang, YC1
Morita, Y1
Hata, K1
Nakanishi, M1
Nishisho, T1
Yura, Y1
Yoneda, T1
Sun, XJ1
Xie, H1
Wang, XK1
Zhang, H1
Song, CX1
Zhang, YJ1
Minter, HA1
Eveson, JW1
Huntley, S1
Elder, DJ1
Hague, A1
Kinugasa, Y1
Hatori, M1
Ito, H1
Kurihara, Y1
Ito, D1
Nagumo, M1
Nystrom, ML1
McCulloch, D1
Weinreb, PH1
Violette, SM1
Speight, PM1
Marshall, JF1
Hart, IR1
Thomas, GJ1

Other Studies

9 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Mouth

ArticleYear
Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma.
    Journal of experimental & clinical cancer research : CR, 2014, May-10, Volume: 33

    Topics: Antigens, CD; Antineoplastic Agents; Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxy

2014
Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1.
    Oncology reports, 2008, Volume: 20, Issue:3

    Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Proliferation; Cyclooxygenas

2008
Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells.
    International journal of cancer, 2012, Jan-01, Volume: 130, Issue:1

    Topics: Animals; Blotting, Western; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cy

2012
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
    Oral diseases, 2012, Volume: 18, Issue:7

    Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Catechin; Cyclooxy

2012
Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2012
[The influence of COX-2 depressant in angiogenesis of oral squamous cell carcinoma].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2012, Volume: 21, Issue:4

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Down-Regulation; Humans; Mo

2012
The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycl

2003
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
    Clinical & experimental metastasis, 2004, Volume: 21, Issue:8

    Topics: Carcinoma, Squamous Cell; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycloox

2004
Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.
    Cancer research, 2006, Nov-15, Volume: 66, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell

2006