n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Cancer of Liver in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (81.82) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Byun, KS; Hwang, JW; Hyun, JJ; Jung, SW; Kim, JH; Koo, JS; Lee, SJ; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Woo, SU; Yeon, JE; Yim, H; Yim, HJ | 1 |
| Gao, B; Li, J; Li, Z; Wang, J; Wang, Y; Xu, H; You, K | 1 |
| Jang, JW | 1 |
| Kim, DW; Kim, EY; Kim, HJ; Kim, SB; Shin, HD; Shin, JE; Shin, KC; Song, IH; Yun, SY | 1 |
| Gong, W; Wang, ZY; Yan, XJ; Yi, TN; Zhang, JL; Zhou, Q | 1 |
| Kim, KT; Kong, SY; Lee, JA; Lee, NO; Lee, YS; Park, JW; Shim, JH | 1 |
| Amuro, Y; Cheng, J; Hada, T; Imanishi, H | 1 |
| Andriantsitohaina, R; Chasserot, S; Mitolo-Chieppa, D; Potenza, MA; Randriamboavonjy, V; Schneider, F; Stoclet, JC; Tabernero, A; Wolf, P | 1 |
| Chan, HL; Cheng, AS; Johnson, PJ; Leung, WK; Sung, JJ; Wong, N | 1 |
| Schmidt, CM; Wang, Y; Wiesenauer, C | 1 |
| Abe, T; Chen, Q; Koyanagi, T; Nonomura, K; Shinohara, N; Watanabe, T | 1 |
| Kelly, CR; Lam, EC; Wolfe, MM; Yao, M; Zhou, W | 1 |
| Hwang, SY; Kim, JC; Kim, JO; Kim, MK; Kwack, MH; Park, MK; Sung, YK | 1 |
| Daly, JM; Freeman, TA; Gaughan, JP; Matsuda, T; Nishikawa, M; Stapleton, PP | 1 |
| Huang, DS; Liang, TB; Shen, KZ; Wei, JF; Xie, HY; Zheng, SS | 1 |
| Fu, SJ; Ma, L; Wang, X; Zhang, LY; Zhang, YC | 1 |
| Kim, CM; Lee, CW; Lee, JA; Park, JE; Park, JW | 1 |
| Hibi, T; Higuchi, H; Kanamori, H; Kumagai, N; Kurita, S; Nakamoto, N; Saito, H; Tada, S; Takaishi, H; Toda, K; Yamada, T | 1 |
| Bae, SH; Baek, JY; Hur, W; Wang, JS; Yoon, SK | 1 |
| Chen, Z; Li, S; Tong, Q; Wang, Q; Wu, Q; Zhang, W | 1 |
| Bae, SH; Jung, ES; Kim, BK; Kim, BS; Kim, DG; Park, YM; Ryu, WS | 1 |
| Abiru, S; Eguchi, K; Hamasaki, K; Ichikawa, T; Ishikawa, H; Migita, K; Nakao, K; Nakata, K; Sakamoto, M; Shigeno, M | 1 |
22 other study(ies) available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Cancer of Liver
| Article | Year |
|---|---|
Synergistic effect of simvastatin plus NS398 on inhibition of proliferation and survival in hepatocellular carcinoma cell line.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2 Inhibitors; Drug Synergism; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; NF-kappa B; Nitrobenzenes; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Simvastatin; Sulfonamides | 2014 |
Madecassoside suppresses proliferation and invasiveness of HGF-induced human hepatocellular carcinoma cells via PKC-cMET-ERK1/2-COX-2-PGE2 pathway.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Centella; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Hep G2 Cells; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Neoplasm Invasiveness; Nitrobenzenes; Protein Kinase C; Proto-Oncogene Proteins c-met; RNA, Small Interfering; Signal Transduction; Sulfonamides; Triterpenes | 2016 |
[Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor].
Topics: Carcinoma, Hepatocellular; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Nitrobenzenes; Sulfonamides; Survivin | 2008 |
[Down-regulation of survivin in growth inhibition of hepatoma cells induced by a selective cyclooxygenase-2 inhibitor].
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; G1 Phase; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Survivin; Time Factors | 2008 |
Lipopolysaccharide initiates a bypass feedback loop of epidermal growth factor receptor signaling by HPS70-induced COX-2 in H22 hepatocarcinoma cells.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; ErbB Receptors; Feedback, Physiological; Female; HSP70 Heat-Shock Proteins; Humans; Inflammation; Lipopolysaccharides; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitrobenzenes; Signal Transduction; Sulfonamides; Toll-Like Receptor 4 | 2011 |
Dual action of a selective cyclooxygenase-2 inhibitor on vascular endothelial growth factor expression in human hepatocellular carcinoma cells: novel involvement of discoidin domain receptor 2.
Topics: Carcinoma, Hepatocellular; Cell Growth Processes; Cell Hypoxia; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Discoidin Domain Receptors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Nitrobenzenes; Promoter Regions, Genetic; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; RNA, Small Interfering; Sulfonamides; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A | 2012 |
NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.
Topics: 6-Ketoprostaglandin F1 alpha; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; G1 Phase; Humans; Isoenzymes; Liver Neoplasms; Membrane Proteins; Nitrobenzenes; Proliferating Cell Nuclear Antigen; Prostaglandin-Endoperoxide Synthases; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S Phase; Sulfonamides; Tumor Cells, Cultured | 2002 |
Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone.
Topics: Adult; Arteries; Blotting, Western; Carcinoma, Hepatocellular; Case-Control Studies; Cyclooxygenase 2; Dilatation, Pathologic; Female; Hepatitis, Viral, Human; Humans; Immunohistochemistry; Indomethacin; Isoenzymes; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Membrane Proteins; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Norepinephrine; Omentum; Prostaglandin-Endoperoxide Synthases; Severity of Illness Index; Sulfonamides; Up-Regulation | 2003 |
Specific COX-2 inhibitor, NS-398, suppresses cellular proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Topics: Annexin A5; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fas Ligand Protein; Fluorescent Dyes; Humans; Isoenzymes; Liver Neoplasms; Membrane Glycoproteins; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides | 2003 |
Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis.
Topics: Adenocarcinoma; Apoptosis; Butadienes; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Humans; Isoenzymes; Liver Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Nitrobenzenes; Pancreatic Neoplasms; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Sulfonamides | 2003 |
Significance of COX-2 expression in human renal cell carcinoma cell lines.
Topics: Animals; Apoptosis; Blotting, Western; Butyrates; Carcinoma, Renal Cell; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclooxygenase 2; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Genetic Vectors; Humans; Immunohistochemistry; Inhibitory Concentration 50; Isoenzymes; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Nitrobenzenes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2004 |
Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer.
Topics: Animals; Blotting, Western; Cell Division; Cell Movement; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Isoenzymes; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured | 2004 |
NS398 inhibits the growth of Hep3B human hepatocellular carcinoma cells via caspase-independent apoptosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Immunoblotting; Indoles; Liver Neoplasms; Nitrobenzenes; Sulfonamides; Time Factors | 2004 |
NS-398 inhibits tumor growth and liver metastasis of colon cancer through induction of apoptosis and suppression of the plasminogen activation system in a mouse model.
Topics: Animals; Apoptosis; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; In Situ Nick-End Labeling; Isoenzymes; Liver Neoplasms; Mice; Mice, Inbred C57BL; Nitrobenzenes; Plasminogen; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A | 2004 |
Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2.
Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Primers; Humans; Liver Neoplasms; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2005 |
[Effects of selective cyclooxygenase-2 inhibitor NS-398 on proliferation and cell cycle progression of hepatocarcinoma cells].
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Humans; Liver Neoplasms; Nitrobenzenes; Sulfonamides; Tumor Cells, Cultured | 2005 |
Cyclooxygenase-2 (COX-2) is directly involved but not decisive in proliferation of human hepatocellular carcinoma cells.
Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Electroporation; Flow Cytometry; Humans; Liver Neoplasms; Membrane Proteins; Nitrobenzenes; RNA, Small Interfering; Sulfonamides; Transfection | 2006 |
Cyclooxygenase-2 inhibitor and interferon-beta synergistically induce apoptosis in human hepatoma cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cyclooxygenase 2 Inhibitors; Drug Synergism; Female; Humans; In Vitro Techniques; Interferon-beta; Liver Neoplasms; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Nude; Nitrobenzenes; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
Selective COX-2 inhibitor, NS-398, suppresses cellular proliferation in human hepatocellular carcinoma cell lines via cell cycle arrest.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Liver Neoplasms; Nitrobenzenes; Sulfonamides | 2007 |
Mechanism of growth inhibitory effects of cyclooxygenase-2 inhibitor-NS398 on cancer cells.
Topics: Apoptosis; Carcinoma; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Nitrobenzenes; Sulfonamides; Survivin | 2008 |
Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Isoenzymes; Liver; Liver Neoplasms; Male; Membrane Proteins; Middle Aged; Neoplasm Staging; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured | 2001 |
Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Hepatocellular; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Isoenzymes; Liver Neoplasms; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Sulfonamides; Transcription Factor AP-1; Tumor Cells, Cultured | 2002 |