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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Brain Edema

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Brain Edema in 4 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Postoperative cerebral edema is a devastating complication in neurosurgical patients."1.46Crotalus helleri venom preconditioning reduces postoperative cerebral edema and improves neurological outcomes after surgical brain injury. ( Gren, ECK; Hayes, WK; Kelln, W; Kim, CH; Lekic, T; McBride, DW; Person, CE; Sherchan, P; Tang, J; Zhang, JH, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, CH1
McBride, DW1
Sherchan, P1
Person, CE1
Gren, ECK1
Kelln, W1
Lekic, T1
Hayes, WK1
Tang, J1
Zhang, JH3
Jadhav, V2
Ostrowski, RP1
Tong, W1
Matus, B1
Jesunathadas, R1
Ayer, R1
Sugawara, T1
Gong, C1
Ennis, SR1
Hoff, JT1
Keep, RF1

Other Studies

4 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Brain Edema

ArticleYear
Crotalus helleri venom preconditioning reduces postoperative cerebral edema and improves neurological outcomes after surgical brain injury.
    Neurobiology of disease, 2017, Volume: 107

    Topics: Animals; Body Water; Brain; Brain Edema; Crotalus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Di

2017
Cyclo-oxygenase-2 mediates hyperbaric oxygen preconditioning-induced neuroprotection in the mouse model of surgical brain injury.
    Stroke, 2009, Volume: 40, Issue:9

    Topics: Animals; Brain Edema; Brain Injuries; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, A

2009
The neuroprotective effects of cyclooxygenase-2 inhibition in a mouse model of aneurysmal subarachnoid hemorrhage.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Animals; Brain Edema; Brain Injuries; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Resp

2011
Inducible cyclooxygenase-2 expression after experimental intracerebral hemorrhage.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Animals; Basal Ganglia; Brain Edema; Cerebral Cortex; Cerebral Hemorrhage; Cerebrovascular Circulati

2001