Page last updated: 2024-11-01

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Bone Loss, Osteoclastic

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Bone Loss, Osteoclastic in 11 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"To understand the involvement of osteoclastogenesis inhibitory factor (OCIF), also called osteoprotegerin (OPG), in the pathogenesis of bone destruction in rheumatoid arthritis (RA), we investigated the cytokine network involved in the production of OCIF by human fibroblast-like synovial (HFLS) cells from a patient with RA."7.71Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. ( Higashio, K; Nakagawa, N; Tsuda, E; Yano, K; Yasuda, H, 2001)
"To understand the involvement of osteoclastogenesis inhibitory factor (OCIF), also called osteoprotegerin (OPG), in the pathogenesis of bone destruction in rheumatoid arthritis (RA), we investigated the cytokine network involved in the production of OCIF by human fibroblast-like synovial (HFLS) cells from a patient with RA."3.71Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. ( Higashio, K; Nakagawa, N; Tsuda, E; Yano, K; Yasuda, H, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krieger, NS2
Bushinsky, DA2
Jang, S1
Bak, EJ1
Kim, M1
Kim, JM1
Chung, WY1
Cha, JH1
Yoo, YJ1
Honda, K1
Collin-Osdoby, P1
Rothe, L1
Bekker, S1
Anderson, F1
Huang, Y1
Osdoby, P1
Ha, H1
Lee, JH1
Kim, HN1
Kim, HM1
Kwak, HB1
Lee, S1
Kim, HH1
Lee, ZH1
Frick, KK1
LaPlante Strutz, K1
Michalenka, A1
Suzuki, Y1
Nishiyama, T1
Hasuda, K1
Fujishiro, T1
Niikura, T1
Hayashi, S1
Hashimoto, S1
Kurosaka, M1
Lader, CS1
Flanagan, AM1
Manabe, N1
Oda, H1
Nakamura, K2
Kuga, Y1
Uchida, S1
Kawaguchi, H2
Chikazu, D1
Kumegawa, M1
Hakeda, Y1
Yano, K1
Nakagawa, N1
Yasuda, H1
Tsuda, E1
Higashio, K1

Other Studies

11 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Bone Loss, Osteoclastic

ArticleYear
Stimulation of fibroblast growth factor 23 by metabolic acidosis requires osteoblastic intracellular calcium signaling and prostaglandin synthesis.
    American journal of physiology. Renal physiology, 2017, Oct-01, Volume: 313, Issue:4

    Topics: Acidosis; Animals; Bone Resorption; Boron Compounds; Calcium Signaling; Fibroblast Growth Factor-23;

2017
Wogonin inhibits osteoclast formation induced by lipopolysaccharide.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:7

    Topics: Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Coculture Techniques; Cyclooxygenas

2010
Interleukin-6 and soluble interleukin-6 receptor suppress osteoclastic differentiation by inducing PGE(2) production in chondrocytes.
    Journal of oral science, 2011, Volume: 53, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Carbonic Anhydrase II; Cathepsin K; Cell D

2011
Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:10

    Topics: Allantois; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Chick Embryo; Chorion; C

2002
alpha-Lipoic acid inhibits inflammatory bone resorption by suppressing prostaglandin E2 synthesis.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Jan-01, Volume: 176, Issue:1

    Topics: Animals; Antioxidants; Blotting, Western; Bone and Bones; Bone Marrow Cells; Bone Resorption; Carrie

2006
Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:6

    Topics: Acidosis; Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Calcium; Cells, Cultured; Cult

2007
Effect of etidronate on COX-2 expression and PGE(2) production in macrophage-like RAW 264.7 cells stimulated by titanium particles.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2007, Volume: 12, Issue:6

    Topics: Animals; Bone Resorption; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitor

2007
Prostaglandin E2, interleukin 1alpha, and tumor necrosis factor-alpha increase human osteoclast formation and bone resorption in vitro.
    Endocrinology, 1998, Volume: 139, Issue:7

    Topics: Antibodies, Monoclonal; Bone Marrow Cells; Bone Resorption; Cell Count; Cell Division; Cyclooxygenas

1998
Involvement of fibroblast growth factor-2 in joint destruction of rheumatoid arthritis patients.
    Rheumatology (Oxford, England), 1999, Volume: 38, Issue:8

    Topics: Animals; Arthritis, Rheumatoid; Bone Resorption; Calcium; Cell Differentiation; Coculture Techniques

1999
Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:3

    Topics: Acid Phosphatase; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bo

2000
Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor.
    Journal of bone and mineral metabolism, 2001, Volume: 19, Issue:6

    Topics: Arthritis, Rheumatoid; Bone Resorption; Cells, Cultured; Culture Media, Conditioned; Dinoprostone; F

2001