n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Bone Cancer in 7 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bone is the most common site for breast cancer spread." | 1.48 | The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis. ( Bendinelli, P; Desiderio, MA; Maroni, P; Matteucci, E, 2018) |
| "Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood." | 1.34 | Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells. ( Choe, M; Choi, EM; Ha, KS; Han, JA; Kim, H; Kim, JI; Kim, SR; Kim, SS; Kim, YM; Lee, EJ; Park, JH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maroni, P | 1 |
| Bendinelli, P | 1 |
| Matteucci, E | 1 |
| Desiderio, MA | 1 |
| Matsuda, T | 1 |
| Kondo, A | 1 |
| Tsunashima, Y | 1 |
| Togari, A | 1 |
| Duan, DP | 1 |
| Dang, XQ | 1 |
| Wang, KZ | 1 |
| Wang, YP | 1 |
| Zhang, H | 1 |
| You, WL | 1 |
| Hiraga, T | 1 |
| Myoui, A | 1 |
| Choi, ME | 1 |
| Yoshikawa, H | 1 |
| Yoneda, T | 1 |
| Lee, EJ | 1 |
| Choi, EM | 1 |
| Kim, SR | 1 |
| Park, JH | 1 |
| Kim, H | 1 |
| Ha, KS | 1 |
| Kim, YM | 1 |
| Kim, SS | 1 |
| Choe, M | 1 |
| Kim, JI | 1 |
| Han, JA | 1 |
| Moalic, S | 1 |
| Liagre, B | 2 |
| Le Bail, JC | 1 |
| Beneytout, JL | 2 |
| Moalic-Juge, S | 1 |
| Duval, R | 1 |
| Corbiere, C | 1 |
| Bianchi, A | 1 |
| Bordji, K | 1 |
| Bosgiraud, C | 1 |
7 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Bone Cancer
| Article | Year |
|---|---|
The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Femal | 2018 |
Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Topics: Adult; Anticoagulants; Bone Neoplasms; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygena | 2010 |
The cyclooxygenase-2 inhibitor NS-398 inhibits proliferation and induces apoptosis in human osteosarcoma cells via downregulation of the survivin pathway.
Topics: Animals; Apoptosis; Bone Neoplasms; Caspase 3; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Down | 2012 |
Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer.
Topics: Animals; Apoptosis; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cyclooxygena | 2006 |
Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells.
Topics: Bone Neoplasms; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Cy | 2007 |
Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor.
Topics: Adenovirus E1A Proteins; Apoptosis; Arachidonic Acid; bcl-2-Associated X Protein; Blotting, Western; | 2001 |
The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bone Neoplasms; Caspase 3; Caspases; Cyclin-Depe | 2002 |