n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Blood Poisoning in 9 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Immune function after experimental hemorrhagic shock and subsequent sepsis may be gender-related, with enhanced immunity and better survival in females." | 1.32 | Inhibition of cyclooxygenase-2 by NS-398 following hemorrhage and subsequent sepsis: no beneficial effects in either gender. ( Brötzmann, K; Kahlke, V; Schafmayer, C; Schröder, J; Seidel, M; Stapela, S, 2004) |
| "Following trauma, increased prostaglandin E2 (PGE2) levels may be important in immunodysregulation." | 1.31 | Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival. ( Concannon, EM; Daly, JM; Mackrell, PJ; Naama, HA; Schaefer, PA; Shaftan, GW; Stapleton, PP; Strong, VE, 2000) |
| "Sepsis was induced in 15-day-old rat pups by intraperitoneal implantation of fecal pellets containing Escherichia coli and Bacteroides fragilis." | 1.31 | Sepsis-induced alteration in T-cell Ca(2+) signaling in neonatal rats. ( Alattar, MH; Choudhry, MA; Dallal, O; Muraskas, JK; Namak, SY; Ravindranath, TM; Sayeed, MM, 2001) |
| "Studies indicate that trauma-hemorrhage results in activation of Kupffer cells to release inflammatory mediators and it leads to immunosuppression and increased susceptibility to subsequent sepsis." | 1.31 | Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis. ( Bland, KI; Chaudry, IH; Cioffi, WG; Diodato, MD; Knöferl, MW; Schwacha, MG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, NC | 1 |
| Cha, JH | 1 |
| Kim, H | 1 |
| Kwak, J | 1 |
| Kim, D | 1 |
| Seo, SH | 1 |
| Shin, JS | 1 |
| Kim, T | 1 |
| Park, KD | 1 |
| Lee, J | 1 |
| No, KT | 1 |
| Kim, YK | 1 |
| Lee, KT | 1 |
| Pae, AN | 1 |
| Chen, J | 1 |
| Cai, S | 1 |
| Li, R | 1 |
| Xie, J | 1 |
| Yang, F | 1 |
| Liu, T | 1 |
| Qiu, G | 1 |
| Zheng, G | 1 |
| Ge, M | 1 |
| Huang, L | 1 |
| Tong, H | 1 |
| Chen, P | 1 |
| Lai, D | 1 |
| Hu, Y | 1 |
| Cheng, B | 1 |
| Shu, Q | 1 |
| Xu, J | 1 |
| Li, B | 1 |
| Li, YM | 1 |
| Li, X | 1 |
| Shi, B | 1 |
| He, MY | 1 |
| Zhu, XL | 1 |
| Zhou, WC | 1 |
| Wachtel, MS | 1 |
| Frezza, E | 1 |
| Tunçtan, B | 1 |
| Altug, S | 1 |
| Uludag, O | 1 |
| Demirkay, B | 1 |
| Abacioglu, N | 1 |
| Kahlke, V | 1 |
| Seidel, M | 1 |
| Stapela, S | 1 |
| Brötzmann, K | 1 |
| Schafmayer, C | 1 |
| Schröder, J | 1 |
| Strong, VE | 1 |
| Mackrell, PJ | 1 |
| Concannon, EM | 1 |
| Naama, HA | 1 |
| Schaefer, PA | 1 |
| Shaftan, GW | 1 |
| Stapleton, PP | 1 |
| Daly, JM | 1 |
| Alattar, MH | 1 |
| Ravindranath, TM | 1 |
| Choudhry, MA | 1 |
| Muraskas, JK | 1 |
| Namak, SY | 1 |
| Dallal, O | 1 |
| Sayeed, MM | 1 |
| Knöferl, MW | 1 |
| Diodato, MD | 1 |
| Schwacha, MG | 1 |
| Cioffi, WG | 1 |
| Bland, KI | 1 |
| Chaudry, IH | 1 |
9 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Blood Poisoning
| Article | Year |
|---|---|
Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.
Topics: Amination; Animals; Anti-Inflammatory Agents; Cell Line; Dinoprostone; Interleukin-1beta; Lipopolysa | 2015 |
Blockade of Cycloxygenase-2 ameliorates sepsis induced immune-suppression by regulating myeloid-derived suppressor cells.
Topics: Animals; CD4-Positive T-Lymphocytes; Cecum; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, | 2022 |
Adipose-derived mesenchymal stem cells modulate CD14
Topics: Adipose Tissue; Aged; Animals; Cells, Cultured; Coculture Techniques; Cohort Studies; Cyclooxygenase | 2017 |
COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Hepatocytes; Homeostasis; Liver D | 2009 |
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Diclofenac; | 2003 |
Inhibition of cyclooxygenase-2 by NS-398 following hemorrhage and subsequent sepsis: no beneficial effects in either gender.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dinopr | 2004 |
Blocking prostaglandin E2 after trauma attenuates pro-inflammatory cytokines and improves survival.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cyclooxygenase 2; Cyclooxygenase 2 In | 2000 |
Sepsis-induced alteration in T-cell Ca(2+) signaling in neonatal rats.
Topics: Animals; Animals, Newborn; Bacteroides Infections; Calcium; Concanavalin A; Cyclooxygenase 1; Cycloo | 2001 |
Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; In | 2001 |