n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Benign Neoplasms in 12 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The selective COX-2 inhibitors NS-398, Celecoxib and Meloxicam and three human glioma cell lines (D384, U251 and U87) were used." | 3.74 | Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration. ( Berg, Jv; Kuipers, GK; Lafleur, MV; Slotman, BJ; Sminia, P; Stoter, TR; Wedekind, LE, 2007) |
| " We report that indomethacin, a nonspecific inhibitor of COX, and NS398, a specific inhibitor of COX2, preserved muscle mass and reduced type 1 TNF receptors in muscles of mice bearing the Lewis lung carcinoma, but not in mice bearing the B16 melanoma." | 3.73 | Inhibitors of COX activity preserve muscle mass in mice bearing the Lewis lung carcinoma, but not the B16 melanoma. ( Graves, E; McCarthy, DO; Ramsay, E, 2006) |
| "However, NSAIDs produce gastroduodenal ulcers in about 25% of users (often with bleeding and/or perforations) and delay ulcer healing, presumably by blocking prostaglandin synthesis from cyclooxygenase (COX)-1 and COX-2 (ref." | 1.30 | Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. ( Itani, RM; Jones, MK; Levin, E; Peskar, BM; Sarfeh, IJ; Tarnawski, AS; Wang, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 1 |
| Shim, M | 1 |
| Ferrario, A | 1 |
| Gomer, CJ | 1 |
| Réti, A | 1 |
| Yamamoto, K | 1 |
| Asano, K | 1 |
| Ito, Y | 1 |
| Matsukawa, N | 1 |
| Kim, S | 1 |
| Yamatodani, A | 1 |
| Bisht, KS | 1 |
| Bradbury, CM | 1 |
| Zoberi, I | 1 |
| Curry, HA | 1 |
| Kaushal, A | 1 |
| Roti Roti, JL | 1 |
| Gius, D | 1 |
| Han, JH | 1 |
| Roh, MS | 1 |
| Park, CH | 1 |
| Park, KC | 1 |
| Cho, KH | 1 |
| Kim, KH | 1 |
| Eun, HC | 1 |
| Chung, JH | 1 |
| Zhong, H | 1 |
| Willard, M | 1 |
| Simons, J | 1 |
| Graves, E | 1 |
| Ramsay, E | 1 |
| McCarthy, DO | 1 |
| Renard, JF | 1 |
| Julémont, F | 1 |
| de Leval, X | 1 |
| Pirotte, B | 1 |
| Jordan, BF | 1 |
| Crokart, N | 1 |
| Baudelet, C | 1 |
| Cron, GO | 1 |
| Ansiaux, R | 1 |
| Gallez, B | 1 |
| Kuipers, GK | 1 |
| Slotman, BJ | 1 |
| Wedekind, LE | 1 |
| Stoter, TR | 1 |
| Berg, Jv | 1 |
| Sminia, P | 1 |
| Lafleur, MV | 1 |
| Jones, MK | 1 |
| Wang, H | 1 |
| Peskar, BM | 1 |
| Levin, E | 1 |
| Itani, RM | 1 |
| Sarfeh, IJ | 1 |
| Tarnawski, AS | 1 |
1 review available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Benign Neoplasms
| Article | Year |
|---|---|
The use of nimesulide and its analogues in cancer chemoprevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Cyclooxygenase 2; Cyclo | 2006 |
11 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Benign Neoplasms
| Article | Year |
|---|---|
COX-2 inhibitor NS-398 suppresses doxorubicin-induced p53 accumulation through inhibition of ROS-mediated Jnk activation.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Doxorubicin; Humans; | 2016 |
Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor.
Topics: Animals; Celecoxib; Cell Line, Tumor; Cell Transformation, Neoplastic; Combined Modality Therapy; Cy | 2010 |
[Application of non-steroidal anti-inflammatory drugs to enhance 5-fluorouracil efficacy in experimental systems].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase | 2010 |
Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats.
Topics: Animals; Anorexia; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Docetaxel; Hypothalamus | 2012 |
Inhibition of cyclooxygenase-2 with NS-398 and the prevention of radiation-induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells.
Topics: Animals; Cell Division; Cell Separation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxy | 2003 |
Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Cellular Senescence; Cyclooxygenase 2; C | 2004 |
NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms.
Topics: Cell Hypoxia; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA-Binding | 2004 |
Inhibitors of COX activity preserve muscle mass in mice bearing the Lewis lung carcinoma, but not the B16 melanoma.
Topics: Analysis of Variance; Animals; Cachexia; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Female; I | 2006 |
Complex relationship between changes in oxygenation status and changes in R*2: the case of insulin and NS-398, two inhibitors of oxygen consumption.
Topics: Animals; Dose-Response Relationship, Drug; Image Interpretation, Computer-Assisted; Insulin; Magneti | 2006 |
Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration.
Topics: Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose | 2007 |
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase | 1999 |