n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Barrett Esophagus in 4 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Barrett Esophagus: A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment of Barrett's esophagus is controversial." | 2.43 | [The clinical strategy for the Barrett's esophagus]. ( Goto, H; Kitabatake, S; Niwa, Y, 2005) |
| "Biopsies from nondysplastic Barrett's esophagus expressed increased gastrin mRNA levels compared with other biopsies." | 1.32 | Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis. ( Abdalla, SI; Fitzgerald, RC; Lao-Sirieix, P; Lovat, LB; Novelli, MR; Sanderson, IR, 2004) |
| "Adenocarcinoma in Barrett's esophagus has been increasing in incidence at a rapid rate for more than two decades." | 1.31 | Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. ( Beer, DG; Cryer, B; Shewmake, K; Souza, RF; Spechler, SJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdalla, SI | 1 |
| Lao-Sirieix, P | 1 |
| Novelli, MR | 1 |
| Lovat, LB | 1 |
| Sanderson, IR | 1 |
| Fitzgerald, RC | 1 |
| Kitabatake, S | 1 |
| Niwa, Y | 1 |
| Goto, H | 1 |
| Ogunwobi, OO | 1 |
| Beales, IL | 1 |
| Souza, RF | 1 |
| Shewmake, K | 1 |
| Beer, DG | 1 |
| Cryer, B | 1 |
| Spechler, SJ | 1 |
1 review available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Barrett Esophagus
| Article | Year |
|---|---|
[The clinical strategy for the Barrett's esophagus].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Ba | 2005 |
3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Barrett Esophagus
| Article | Year |
|---|---|
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Benzodiazepines; Blot | 2004 |
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Caspase 3; Cell Divisio | 2008 |
Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Barrett Esophagus; Cell Division | 2000 |