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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Bacterial Disease

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Bacterial Disease in 6 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"On Day 7 after trauma, mice were sacrificed, serum was collected, and splenic macrophages were evaluated for PGE(2), LTB(4), IL-6, TNF-alpha, and NO production."1.31NS-398 treatment after trauma modifies NF-kappaB activation and improves survival. ( Concannon, EM; Daly, JM; Mack Strong, VE; Mackrell, PJ; Mestre, JR; Schaefer, PA; Smyth, GP; Stapleton, PP, 2001)
"This hyperalgesia was observed only in the period before the development of fever which started 120-135 min after the LPS injection."1.31Prostanoids in the preoptic hypothalamus mediate systemic lipopolysaccharide-induced hyperalgesia in rats. ( Abe, M; Hori, T; Oka, T; Takahashi, S, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qian, X1
Zhang, J1
Liu, J1
Shoup, M1
He, LK1
Liu, H1
Shankar, R1
Gamelli, R1
Mack Strong, VE1
Mackrell, PJ1
Concannon, EM1
Mestre, JR1
Smyth, GP1
Schaefer, PA1
Stapleton, PP1
Daly, JM1
Reddy, RC1
Chen, GH1
Tateda, K1
Tsai, WC1
Phare, SM1
Mancuso, P1
Peters-Golden, M1
Standiford, TJ1
Abe, M1
Oka, T1
Hori, T1
Takahashi, S1
Schwacha, MG1
Chung, CS1
Ayala, A1
Bland, KI1
Chaudry, IH1

Other Studies

6 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Bacterial Disease

ArticleYear
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway.
    The Journal of biological chemistry, 2011, Jan-21, Volume: 286, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Cell Line; Chemokine CCL5; C

2011
Cyclooxygenase-2 inhibitor NS-398 improves survival and restores leukocyte counts in burn infection.
    The Journal of trauma, 1998, Volume: 45, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Burns; Cyclooxygenase Inhibi

1998
NS-398 treatment after trauma modifies NF-kappaB activation and improves survival.
    The Journal of surgical research, 2001, Jun-01, Volume: 98, Issue:1

    Topics: Animals; Bacterial Infections; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibit

2001
Selective inhibition of COX-2 improves early survival in murine endotoxemia but not in bacterial peritonitis.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:3

    Topics: Animals; Bacterial Infections; Body Temperature Regulation; Cecum; Cyclooxygenase 2; Cyclooxygenase

2001
Prostanoids in the preoptic hypothalamus mediate systemic lipopolysaccharide-induced hyperalgesia in rats.
    Brain research, 2001, Oct-19, Volume: 916, Issue:1-2

    Topics: Animals; Bacterial Infections; Body Temperature; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase

2001
Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury.
    American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:2

    Topics: Animals; Bacterial Infections; Burns; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase

2002