n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Autoimmune Diabetes in 5 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease believed to be caused by an inflammatory process in the pancreas leading to selective destruction of the beta cells." | 1.31 | COX-2 inhibition prevents insulin-dependent diabetes in low-dose streptozotocin-treated mice. ( Floyd, RA; Jacob, JM; Kotake, Y; Tabatabaie, T; Waldon, AM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nacci, C | 1 |
| Tarquinio, M | 1 |
| De Benedictis, L | 1 |
| Mauro, A | 1 |
| Zigrino, A | 1 |
| Carratù, MR | 1 |
| Quon, MJ | 1 |
| Montagnani, M | 1 |
| Nasrallah, R | 1 |
| Robertson, SJ | 1 |
| Hébert, RL | 1 |
| Tabatabaie, T | 2 |
| Vasquez-Weldon, A | 1 |
| Moore, DR | 1 |
| Kotake, Y | 2 |
| Litherland, SA | 1 |
| Xie, XT | 1 |
| Hutson, AD | 1 |
| Wasserfall, C | 1 |
| Whittaker, DS | 1 |
| She, JX | 1 |
| Hofig, A | 1 |
| Dennis, MA | 1 |
| Fuller, K | 1 |
| Cook, R | 1 |
| Schatz, D | 1 |
| Moldawer, LL | 1 |
| Clare-Salzler, MJ | 1 |
| Waldon, AM | 1 |
| Jacob, JM | 1 |
| Floyd, RA | 1 |
5 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Experime | 2009 |
Chronic COX inhibition reduces diabetes-induced hyperfiltration, proteinuria, and renal pathological markers in 36-week B6-Ins2(Akita) mice.
Topics: Albuminuria; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Body Weight; Creatinine; | 2009 |
Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2.
Topics: Animals; Antineoplastic Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibi | 2003 |
Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell defect for insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Alleles; Antigen-Presenting Cells; Autoantibodies; Case-Control Studies; Ch | 1999 |
COX-2 inhibition prevents insulin-dependent diabetes in low-dose streptozotocin-treated mice.
Topics: Animals; Blood Glucose; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Di | 2000 |