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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Atherogenesis

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Atherogenesis in 3 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
" The finding that LSS-dependent reduction of TNF-alpha generation and HO-1 induction were abrogated by the selective inhibitor of COX-2 NS-398, the nonselective COX inhibitor aspirin, or the specific prostacyclin receptor (IP) antagonist RO3244794 illuminates the central role played by LSS-induced COX-2-dependent prostacyclin in restraining endothelial inflammation."3.75Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. ( Dercho, RA; Di Francesco, A; Di Francesco, L; Dovizio, M; Evangelista, V; Pandolfi, A; Patrignani, P; Piccoli, A; Salvatore, T; Seta, F; Totani, L, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friesen, RW1
Mancini, JA1
Di Francesco, L1
Totani, L1
Dovizio, M1
Piccoli, A1
Di Francesco, A1
Salvatore, T1
Pandolfi, A1
Evangelista, V1
Dercho, RA1
Seta, F1
Patrignani, P1
Taketa, K1
Matsumura, T1
Yano, M1
Ishii, N1
Senokuchi, T1
Motoshima, H1
Murata, Y1
Kim-Mitsuyama, S1
Kawada, T1
Itabe, H1
Takeya, M1
Nishikawa, T1
Tsuruzoe, K1
Araki, E1

Other Studies

3 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Atherogenesis

ArticleYear
Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Fever; Humans; Intramolecular Oxi

2008
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
    Circulation research, 2009, Feb-27, Volume: 104, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Atherosclerosis; Benzofurans; Cells, Cultured; Cyclooxygenase

2009
Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.
    The Journal of biological chemistry, 2008, Apr-11, Volume: 283, Issue:15

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors;

2008