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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Anoxemia

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Anoxemia in 12 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen sulfide (H(2)S) has been shown to protect against oxidative stress injury and inflammation in various hypoxia-induced insult models."7.77Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. ( Chen, P; Dong, Q; Feng, J; Lan, A; Wang, C; Wang, X; Yang, C; Yang, Z; Zeng, F; Zhang, M, 2011)
"Hydrogen sulfide (H(2)S) has been shown to protect against oxidative stress injury and inflammation in various hypoxia-induced insult models."3.77Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. ( Chen, P; Dong, Q; Feng, J; Lan, A; Wang, C; Wang, X; Yang, C; Yang, Z; Zeng, F; Zhang, M, 2011)
"After the anoxia treatment, each group was reoxygenated in a mixture of 95% air and 5% CO2 incubator for 6 h."1.34Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells. ( Han, BS; Huang, JH; Shi, LB, 2007)
"Addition of PGE(2) to PC-3ML human prostate cancer cells had no effect on HIF-1alpha mRNA levels."1.31Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. ( Dosoretz, A; Holland, JF; Kirschenbaum, A; Levine, AC; Liu, XH; Lu, M; Yao, S, 2002)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (75.00)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Anoopkumar-Dukie, S1
Conere, T1
Houston, A1
King, L1
Christie, D1
McDermott, C1
Allshire, A1
Huxtable, AG1
Kopp, E1
Dougherty, BJ1
Watters, JJ1
Mitchell, GS1
Yang, C1
Yang, Z1
Zhang, M1
Dong, Q1
Wang, X1
Lan, A1
Zeng, F1
Chen, P1
Wang, C1
Feng, J1
Liu, XH1
Kirschenbaum, A1
Lu, M1
Yao, S1
Dosoretz, A1
Holland, JF1
Levine, AC1
Li, RC1
Row, BW1
Gozal, E1
Kheirandish, L1
Fan, Q1
Brittian, KR1
Guo, SZ1
Sachleben, LR1
Gozal, D1
Palayoor, ST1
Tofilon, PJ1
Coleman, CN1
Gendron, TF1
Brunette, E1
Mealing, GA1
Nguyen, A1
Tauskela, JS1
Morley, P1
Saed, GM1
Munkarah, AR1
Abu-Soud, HM1
Diamond, MP2
Saed, G1
Shi, LB1
Huang, JH1
Han, BS1
Park, MK1
Kim, CH1
Kim, YM1
Kang, YJ1
Kim, HJ2
Seo, HG1
Lee, JH1
Chang, KC1
Malek, A1
Sager, R1
Schneider, H1

Other Studies

12 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Anoxemia

ArticleYear
The COX-2 inhibitor NS398 selectively sensitizes hypoxic HeLa cells to ionising radiation by mechanisms both dependent and independent of COX-2.
    Prostaglandins & other lipid mediators, 2020, Volume: 148

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Survival; Cyclooxygenase 2; Female; HeLa Ce

2020
Cyclooxygenase enzyme activity does not impair respiratory motor plasticity after one night of intermittent hypoxia.
    Respiratory physiology & neurobiology, 2018, Volume: 256

    Topics: Animals; Carbon Dioxide; CD11b Antigen; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypoxia;

2018
Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Cobalt; Cyclooxygenase 2; Cyclooxygenase Inhibit

2011
Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line.
    The Journal of biological chemistry, 2002, Dec-20, Volume: 277, Issue:51

    Topics: Active Transport, Cell Nucleus; Arachidonic Acid; Catalysis; Cell Nucleus; Culture Media, Serum-Free

2002
Cyclooxygenase 2 and intermittent hypoxia-induced spatial deficits in the rat.
    American journal of respiratory and critical care medicine, 2003, Aug-15, Volume: 168, Issue:4

    Topics: Analysis of Variance; Animals; Apoptosis; Cerebral Cortex; Cyclooxygenase 1; Cyclooxygenase 2; Cyclo

2003
Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-01, Volume: 9, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tu

2003
Opposing effects of cyclooxygenase-2 selective inhibitors on oxygen-glucose deprivation-induced neurotoxicity.
    European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3

    Topics: Animals; Calcium; Canada; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Cyclooxyge

2004
Hypoxia upregulates cyclooxygenase-2 and prostaglandin E(2) levels in human peritoneal fibroblasts.
    Fertility and sterility, 2005, Volume: 83 Suppl 1

    Topics: Cell Survival; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc

2005
Modulation of the expression of peroxisome proliferators-activated receptors in human fibroblasts.
    Fertility and sterility, 2007, Volume: 87, Issue:3

    Topics: Cyclooxygenase 2 Inhibitors; Dichloroacetic Acid; Female; Fibroblasts; Humans; Hypoxia; Nitrobenzene

2007
Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells.
    World journal of gastroenterology, 2007, Apr-28, Volume: 13, Issue:16

    Topics: Cell Line; Cell Survival; Cold Temperature; Endothelium, Vascular; Gene Expression Regulation; Human

2007
Akt-dependent heme oxygenase-1 induction by NS-398 in C6 glial cells: a potential role for CO in prevention of oxidative damage from hypoxia.
    Neuropharmacology, 2007, Volume: 53, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbon Monoxide; Cell Line; Enzyme Indu

2007
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Adult; Cell Hypoxia; Chorionic Villi; Culture Techniques; Cyclooxygenase Inhibitors; Cytokines; Drug

2001