n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Aging in 9 studies
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glycine treatment improved this modulator effect and increased relaxation to acetylcholine." | 1.42 | Vascular endothelial function is improved by oral glycine treatment in aged rats. ( Cruz, M; García-Macedo, R; Gómez-Zamudio, JH; Ibarra-Barajas, M; Kumate, J; Lázaro-Suárez, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez-Zamudio, JH | 1 |
| García-Macedo, R | 1 |
| Lázaro-Suárez, M | 1 |
| Ibarra-Barajas, M | 1 |
| Kumate, J | 1 |
| Cruz, M | 1 |
| Gao, Q | 1 |
| Zhan, P | 1 |
| Alander, CB | 1 |
| Kream, BE | 1 |
| Hao, C | 1 |
| Breyer, MD | 1 |
| Pilbeam, CC | 2 |
| Raisz, LG | 2 |
| Armstrong, SJ | 1 |
| Zhang, Y | 1 |
| Stewart, KG | 1 |
| Davidge, ST | 1 |
| Mukai, Y | 1 |
| Shimokawa, H | 1 |
| Higashi, M | 1 |
| Morikawa, K | 1 |
| Matoba, T | 1 |
| Hiroki, J | 1 |
| Kunihiro, I | 1 |
| Talukder, HM | 1 |
| Takeshita, A | 1 |
| Armstead, WM | 1 |
| Gahring, LC | 1 |
| Persiyanov, K | 1 |
| Days, EL | 1 |
| Rogers, SW | 1 |
| Briones, AM | 1 |
| Montoya, N | 1 |
| Giraldo, J | 1 |
| Vila, E | 1 |
| Peri, KG | 1 |
| Hardy, P | 1 |
| Li, DY | 1 |
| Varma, DR | 1 |
| Chemtob, S | 1 |
| Tai, H | 1 |
| Miyaura, C | 1 |
| Tamura, T | 1 |
| Ohsugi, Y | 1 |
| Koishihara, Y | 1 |
| Kubodera, N | 1 |
| Kawaguchi, H | 1 |
| Suda, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlled and Randomized Clinical Trial for Evaluating the Effect of a Supplement of Glycine as Adjuvant in the Treatment of COVID-19 Pneumonia in Patients Initiating Mechanical Ventilation[NCT04443673] | 59 participants (Actual) | Interventional | 2020-06-15 | Terminated (stopped due to An interim analysis showed no difference in major outcomes (n=35 glycine and n=24 control participants)) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Aging
| Article | Year |
|---|---|
Vascular endothelial function is improved by oral glycine treatment in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Endothelium, Vascular; Gly | 2015 |
Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.
Topics: Aging; Animals; Body Composition; Bone and Bones; Breeding; Cells, Cultured; Dinoprostone; Female; G | 2009 |
Estrogen replacement reduces PGHS-2-dependent vasoconstriction in the aged rat.
Topics: Aging; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Estradiol; | 2002 |
Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bridged Bicyclo Com | 2002 |
Cyclooxygenase-2-dependent superoxide generation contributes to age-dependent impairment of G protein-mediated cerebrovasodilation.
Topics: Aging; Animals; Animals, Newborn; Arteries; Blood Chemical Analysis; Brain Injuries; Catalase; Cereb | 2003 |
Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPAR gamma expression and is altered by long-term NS398 administration.
Topics: Aging; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hippocampu | 2005 |
Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries.
Topics: Acetylcholine; Aging; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Int | 2005 |
Prostaglandin G/H synthase-2 is a major contributor of brain prostaglandins in the newborn.
Topics: Aging; Animals; Animals, Newborn; Base Sequence; Brain; Cerebral Cortex; Cyclooxygenase Inhibitors; | 1995 |
Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation.
Topics: Aging; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Blotting, N | 1997 |