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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Acute Confusional Senile Dementia

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Acute Confusional Senile Dementia in 7 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Research Excerpts

ExcerptRelevanceReference
"To evaluate their potential use against Alzheimer's disease, in vitro evaluation of β-amyloid fibril formation using Aβ(1-40) and Aβ(1-42) peptides was performed."1.421,2-Diaryl-2-hydroxyiminoethanones as dual COX-1 and β-amyloid aggregation inhibitors: biological evaluation and in silico study. ( Ahangar, N; Ahmadnejad, M; Dadashpour, S; Emami, S; Irannejad, H; Ozadali, K; Tuylu Kucukkilinc, T; Unsal Tan, O, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Irannejad, H1
Unsal Tan, O1
Ozadali, K1
Dadashpour, S1
Tuylu Kucukkilinc, T1
Ahangar, N1
Ahmadnejad, M1
Emami, S1
Wang, P2
Guan, PP2
Yu, X2
Zhang, LC1
Su, YN1
Wang, ZY2
Guo, JW1
Cao, LL1
Xu, GB1
Wang, Y1
Paris, D2
Townsend, KP1
Obregon, DF1
Humphrey, J1
Mullan, M2
Quadros, A1
Patel, N1
Crescentini, R1
Crawford, F1
Ferrera, P1
Arias, C1
Narlawar, R1
Pérez Revuelta, BI1
Haass, C1
Steiner, H1
Schmidt, B1
Baumann, K1

Other Studies

7 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Acute Confusional Senile Dementia

ArticleYear
1,2-Diaryl-2-hydroxyiminoethanones as dual COX-1 and β-amyloid aggregation inhibitors: biological evaluation and in silico study.
    Chemical biology & drug design, 2015, Volume: 85, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclo

2015
Prostaglandin I₂ Attenuates Prostaglandin E₂-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism.
    Scientific reports, 2016, Feb-12, Volume: 6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Cell Nucleus; Dinoprostone; Di

2016
Prostaglandin I2 upregulates the expression of anterior pharynx-defective-1α and anterior pharynx-defective-1β in amyloid precursor protein/presenilin 1 transgenic mice.
    Aging cell, 2016, Volume: 15, Issue:5

    Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; C

2016
Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.
    Prostaglandins & other lipid mediators, 2002, Volume: 70, Issue:1-2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cattle; Cells, Cultured; Cyclooxygenase 2;

2002
Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice.
    Neuroscience letters, 2003, Dec-15, Volume: 353, Issue:1

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Brain; Cy

2003
Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells.
    Neurochemistry international, 2005, Volume: 47, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line,

2005
Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Anti-Inflammatory Ag

2006