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n-(2-chloroethyl)-n-nitrosoacetamide and Brain Neoplasms

n-(2-chloroethyl)-n-nitrosoacetamide has been researched along with Brain Neoplasms in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bataille, B; Blanc, JL; Chantereau, T; Guilhot, J; Karayan-Tapon, L; Kusy, S; Lapierre, F; Larsen, CJ; Wager, M1
Nagane, M1
Chen, ZP; Garcia, Y; Langleben, A; Malapetsa, A; Mohr, G; Panasci, LC; Tampieri, D; Yarosh, D1
Kohda, K; Mineura, K; Takahashi, M; Watanabe, K1
Ali-Osman, F; Berger, MS; Griffin, B; Livingston, RB; Spence, AM1
Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ1

Reviews

1 review(s) available for n-(2-chloroethyl)-n-nitrosoacetamide and Brain Neoplasms

ArticleYear
[Chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Drug Resistance, Neoplasm; Glioma; Humans; Nitroso Compounds; Survival Rate; Temozolomide; Tumor Suppressor Proteins

2007

Trials

2 trial(s) available for n-(2-chloroethyl)-n-nitrosoacetamide and Brain Neoplasms

ArticleYear
Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas.
    Journal of neuro-oncology, 2004, Volume: 68, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Middle Aged; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Treatment Outcome

2004
Phase II evaluation of high-dose intravenous cisplatin for treatment of adult malignant gliomas recurrent after chloroethylnitrosourea failure.
    Journal of neuro-oncology, 1992, Volume: 12, Issue:2

    Topics: Adult; Brain Neoplasms; Cisplatin; Drug Evaluation; Female; Glioma; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Nitroso Compounds

1992

Other Studies

3 other study(ies) available for n-(2-chloroethyl)-n-nitrosoacetamide and Brain Neoplasms

ArticleYear
Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1999, Volume: 26, Issue:2

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; Drug Resistance, Neoplasm; Female; Glioma; Guanine; Humans; Male; Middle Aged; Nitroso Compounds; Tumor Cells, Cultured

1999
O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:1

    Topics: Animals; Benzyl Compounds; Brain Neoplasms; Cell Division; DNA Damage; DNA, Neoplasm; Guanine; Mice; Mice, Nude; Nimustine; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Transplantation, Heterologous

2000
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship

1986